Epidemics of serogroup a Neisseria meningitidis of subgroup III in Africa, 1989-94

被引：40

作者：

Guibourdenche, M

Hoiby, EA

Riou, JY

Varaine, F

Joguet, C

Caugant, DA

机构：

[1] NATL INST PUBL HLTH,WHO,COLLABORATING CTR REFERENCE & RES MENINGOCOCCI,N-0462 OSLO,NORWAY

[2] INST PASTEUR,PARIS,FRANCE

[3] EPICTR,PARIS,FRANCE

[4] MED SANS FRONTIERS,BRUSSELS,BELGIUM

来源：

EPIDEMIOLOGY AND INFECTION | 1996年 / 116卷 / 02期

关键词：

D O I：

10.1017/S095026880005233X

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

A total of 125 strains of Neisseria meningitidis recovered in the course of outbreaks from patients with systemic disease in 11 African countries between 1989 and 1994 were analysed by serogrouping, serotyping and multilocus enzyme electrophoresis. Of the 125 patient strains 115 (92 %) belonged to the clone-complex of serogroup A meningococci, designated subgroup III. Among the remaining strains, 4 were also serogroup A, but belonged to the clonal groups I and IV-1 (2 strains each), whilst 6 strains (4 serogroup C and 2 serogroup W135) represented clones of the ET-37 complex. Our results indicated that the second pandemic caused by clones of subgroup III is still spreading in Africa. Towards the West it has reached Niger, Mall, Guinea and The Gambia, and towards the South, the Central African Republic, Uganda, Rwanda, Burundi, Tanzania and Zambia.

引用

页码：115 / 120

页数：6

共 31 条

[1]

Achtman M., 1990, Reviews in Medical Microbiology, V1, P29

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