Rotavirus serotype G9 is associated with more-severe disease in Latin America

被引：49

作者：

Linhares, A. C.

Verstraeten, Thomas

den Bosch, Judith Wolleswinkel-Van

Clemens, Ralf

Breuer, Thomas

机构：

[1] Inst Evandro Chagas, Secretaria Vigilancia Saude, Minist Saude, Belem, Para, Brazil

[2] GlaxoSmithKline Biol, Rio De Janeiro, Brazil

[3] GlaxoSmithKline Biol, Rixensart, Belgium

[4] Pallas Hlth Res & Consultancy, Rotterdam, Netherlands

来源：

CLINICAL INFECTIOUS DISEASES | 2006年 / 43卷 / 03期

关键词：

D O I：

10.1086/505493

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The association between rotavirus serotypes and severity is not well established. Analysis of a clinical trial conducted in Latin America points at more-severe disease associated with serotype G9. Thus, demonstration of efficacy against G9 will be an important asset of any rotavirus vaccine to be introduced into a Latin American country or any country where G9 has been shown to be prevalent.

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收藏

页码：312 / 314

页数：3

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