The shikimate pathway .9. Halogenation at C-3 of the shikimate nucleus

被引：24

作者：

Brettle, R

Cross, R

Frederickson, M

Haslam, E

MacBeath, FS

Davies, GM

机构：

[1] UNIV SHEFFIELD,DEPT CHEM,SHEFFIELD S3 7HF,S YORKSHIRE,ENGLAND

[2] ZENECA PHARMACEUT,MACCLESFIELD SK10 4TG,CHESHIRE,ENGLAND

来源：

TETRAHEDRON | 1996年 / 52卷 / 31期

关键词：

D O I：

10.1016/0040-4020(96)00574-1

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The use of (-)-shikimic acid as starting material in the syntheses of a series of C-3 halogenated derivatives including the analogous 3 alpha- and 3 beta-fluoro and 3 beta-chloro acids is described together with the first stereospecific synthesis of (-)-3-epi-shikimic acid directly from the parent acid. Copyright (C) 1996 Elsevier Science Ltd

引用

页码：10547 / 10556

页数：10

共 24 条

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