The inflammasome: First line of the immune response to cell stress

被引：381

作者：

Ogura, Yasunori

Sutterwala, Fayyaz S.

Flavell, Richard A.

机构：

[1] Yale Univ, Sch Med, Immunobiol Sect, New Haven, CT 06520 USA

[2] Yale Univ, Sch Med, Howard Hughes Med Inst, New Haven, CT 06520 USA

[3] Yale Univ, Sch Med, Infect Dis Sect, New Haven, CT 06520 USA

来源：

CELL | 2006年 / 126卷 / 04期

关键词：

D O I：

10.1016/j.cell.2006.08.002

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：659 / 662

页数：4

共 24 条

[1] NALP3 forms an IL-lβ-Processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder [J].

Agostini, L ;

Martinon, F ;

Burns, K ;

McDermott, MF ;

Hawkins, PN ;

Tschopp, J .

IMMUNITY, 2004, 20 (03) :319-325

[2] Nalp1b controls mouse macrophage susceptibility to anthrax lethal toxin [J].

Boyden, ED ;

Dietrich, WF .

NATURE GENETICS, 2006, 38 (02) :240-244

[3]

Dinarello CA, 2002, CLIN EXP RHEUMATOL, V20, pS1

[4] The P2X7 receptor:: A key player in IL-1 processing and release [J].

Ferrari, Davide ;

Pizzirani, Cinzia ;

Adinolfi, Elena ;

Lemoli, Roberto M. ;

Curti, Antonio ;

Idzko, Marco ;

Panther, Elisabeth ;

Di Virgilio, Francesco .

JOURNAL OF IMMUNOLOGY, 2006, 176 (07) :3877-3883

[5] Cytosolic flagellin requires Ipaf for activation of caspase-1 and interleukin 1β in salmonella-infected macrophages [J].

Franchi, Luigi ;

Amer, Amal ;

Body-Malapel, Mathilde ;

Kanneganti, Thirumala-Devi ;

Ozoren, Nesrin ;

Jagirdar, Rajesh ;

Inohara, Naohiro ;

Vandenabeele, Peter ;

Bertin, John ;

Coyle, Anthony ;

Grant, Ethan P. ;

Nunez, Gabriel .

NATURE IMMUNOLOGY, 2006, 7 (06) :576-582

[6] A poxvirus-encoded pyrin domain protein interacts with ASC-1 to inhibit host inflammatory and apoptotic responses to infection [J].

Johnston, JB ;

Barrett, JW ;

Nazarian, SH ;

Goodwin, M ;

Ricuttio, D ;

Wang, G ;

McFadden, G .

IMMUNITY, 2005, 23 (06) :587-598

[7] Bacterial RNA and small antiviral compounds activate caspase-1 through cryopyrin/Nalp3 [J].

Kanneganti, TD ;

Özören, N ;

Body-Malapel, M ;

Amer, A ;

Park, JH ;

Franchi, L ;

Whitfield, J ;

Barchet, W ;

Colonna, M ;

Vandenabeele, P ;

Bertin, J ;

Coyle, A ;

Grant, EP ;

Akira, S ;

Núñez, G .

NATURE, 2006, 440 (7081) :233-236

[8] Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf [J].

Mariathasan, S ;

Newton, K ;

Monack, DM ;

Vucic, D ;

French, DM ;

Lee, WP ;

Roose-Girma, M ;

Erickson, S ;

Dixit, VM .

NATURE, 2004, 430 (6996) :213-218

[9]

Mariathasan S, 2006, NATURE, V440, P228, DOI 10.1038/nature04515

[10] Identification of bacterial muramyl dipeptide as activator of the NALP3/cryopyrin inflammasome [J].

Martinon, F ;

Agostini, L ;

Meylan, E ;

Tschopp, J .

CURRENT BIOLOGY, 2004, 14 (21) :1929-1934

← 1 2 3 →