Circulating levels of ghrelin and GLP-1 are inversely related during glucose ingestion

被引:39
作者
Djurhuus, CB
Hansen, TK
Gravholt, C
Orskov, L
Hosoda, H
Kangawa, K
Jorgensen, JOL
Holst, JJ
Schmitz, O
机构
[1] Aarhus Univ Hosp, Med Dept Endocrinol & Diabet M, DK-8000 Aarhus, Denmark
[2] Univ Aarhus, Dept Clin Pharmacol, Aarhus, Denmark
[3] Univ Copenhagen, Panum Inst, Dept Med Physiol, DK-2200 Copenhagen N, Denmark
[4] Natl Cardiovasc Ctr, Res Inst, Dept Biochem, Osaka, Japan
关键词
D O I
10.1055/s-2002-33475
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
[No abstract available]
引用
收藏
页码:411 / 413
页数:3
相关论文
共 16 条
  • [1] Endocrine activities of ghrelin, a natural growth hormone secretagogue (GHS), in humans: Comparison and interactions with hexarelin, a nonnatural peptidyl GHS, and GH-releasing hormone
    Arvat, E
    Maccario, M
    Di Vito, L
    Broglio, F
    Benso, A
    Gottero, C
    Papotti, M
    Muccioli, G
    Dieguez, C
    Casanueva, FF
    Deghenghi, R
    Camanni, F
    Ghigo, E
    [J]. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2001, 86 (03) : 1169 - 1174
  • [2] BERLIN E, 2001, J CLIN ENDOCR METAB, V86, P1229
  • [3] A preprandial rise in plasma ghrelin levels suggests a role in meal initiation in humans
    Cummings, DE
    Purnell, JQ
    Frayo, RS
    Schmidova, K
    Wisse, BE
    Weigle, DS
    [J]. DIABETES, 2001, 50 (08) : 1714 - 1719
  • [4] Peripheral versus central effects of glucagon-like peptide-1 receptor agonists on satiety and body weight loss in Zucker obese rats
    de Fonseca, FR
    Navarro, M
    Alvarez, E
    Roncero, I
    Chowen, JA
    Maestre, O
    Gómez, R
    Muñoz, RM
    Eng, J
    Blázquez, E
    [J]. METABOLISM-CLINICAL AND EXPERIMENTAL, 2000, 49 (06): : 709 - 717
  • [5] Glucagon-like peptide 1 promotes satiety and suppresses energy intake in humans
    Flint, A
    Raben, A
    Astrup, A
    Holst, JJ
    [J]. JOURNAL OF CLINICAL INVESTIGATION, 1998, 101 (03) : 515 - 520
  • [6] Ghrelin and des-acyl ghrelin: Two major forms of rat ghrelin peptide in gastrointestinal tissue
    Hosoda, H
    Kojima, M
    Matsuo, H
    Kangawa, K
    [J]. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2000, 279 (03) : 909 - 913
  • [7] Ghrelin is a growth-hormone-releasing acylated peptide from stomach
    Kojima, M
    Hosoda, H
    Date, Y
    Nakazato, M
    Matsuo, H
    Kangawa, K
    [J]. NATURE, 1999, 402 (6762) : 656 - 660
  • [8] Ghrelin stimulates gastric acid secretion and motility in rats
    Masuda, Y
    Tanaka, T
    Inomata, N
    Ohnuma, N
    Tanaka, S
    Itoh, Z
    Hosoda, H
    Kojima, M
    Kangawa, K
    [J]. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2000, 276 (03) : 905 - 908
  • [9] A role for ghrelin in the central regulation of feeding
    Nakazato, M
    Murakami, N
    Date, Y
    Kojima, M
    Matsuo, H
    Kangawa, K
    Matsukura, S
    [J]. NATURE, 2001, 409 (6817) : 194 - 198
  • [10] TISSUE AND PLASMA-CONCENTRATIONS OF AMIDATED AND GLYCINE-EXTENDED GLUCAGON-LIKE PEPTIDE-I IN HUMANS
    ORSKOV, C
    RABENHOJ, L
    WETTERGREN, A
    KOFOD, H
    HOLST, JJ
    [J]. DIABETES, 1994, 43 (04) : 535 - 539