Pathogen inducible voltage-dependent anion channel (AtVDAC) isoforms are localized to mitochondria membrane in Arabidopsis

被引：59

作者：

Lee, Sang Min ^{[1
,2
]}

Hoang, My Hanh Thi ^{[1
]}

Han, Hay Ju ^{[1
,2
]}

Kim, Ho Soo ^{[1
,2
]}

Lee, Kyunghee ^{[1
,2
]}

Kim, Kyung Eun ^{[2
]}

Kim, Doh Hoon ^{[3
]}

Lee, Sang Yeol ^{[1
,2
]}

Chung, Woo Sik ^{[1
,2
]}

机构：

[1] Gyeongsang Natl Univ, Plant Mol Biol & Biotechnol Res Ctr, Brain Korea Program 21, Div Appl Life Sci, Jinju 660701, South Korea

[2] Gyeongsang Natl Univ, Environm Biotechnol Natl Core Res Ctr, Jinju 660701, South Korea

[3] Dona A Univ, Fac Plant Biotechnol, Pusan 604714, South Korea

来源：

MOLECULES AND CELLS | 2009年 / 27卷 / 03期

关键词：

Arabidopsis; mitochondria; outer membrane; pathogen; voltage-dependent anion channel; CELL-DEATH; VDAC; PLANT; IDENTIFICATION; EXPRESSION; CA2+-ATPASE; APOPTOSIS; PROTEINS; DISEASE; STRESS;

D O I：

10.1007/s10059-009-0041-z

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Voltage-dependent anion channels (VDACs) are reported to be porin-type, beta-barrel diffusion pores. They are prominently localized in the outer mitochondrial membrane and are involved in metabolite exchange between the organelle and the cytosol. In this study, we have investigated a family of VDAC isoforms in Arabidopsis thaliana (AtVDAC). We have shown that the heterologous expression of AtVDAC proteins can functionally complement a yeast mutant lacking the endogenous mitochondrial VDAC gene. AtVDACs tagged with GFP were localized to mitochondria in both yeast and plant cells. We also looked at the response of AtVDACs to biotic and abiotic stresses and found that four AtVDAC transcripts were rapidly up-regulated in response to a bacterial pathogen.

引用

页码：321 / 327

页数：7

共 38 条

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