Extending Pummerer reaction chemistry. Application to the oxidative cyclization of indole derivatives

被引：46

作者：

Feldman, KS ^{[1
]}

Vidulova, DB ^{[1
]}

机构：

[1] Penn State Univ, Dept Chem, University Pk, PA 16802 USA

来源：

ORGANIC LETTERS | 2004年 / 6卷 / 11期

关键词：

D O I：

10.1021/ol0493406

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Treatment of 2-(phenylsulfinyl)indoles bearing a pendant nucleophile at C(3) with Tf2O/lutidine triggers a Pummerer-like cyclization to furnish 3,3-spirocyclic-2-(phenyithio)indolenine products, which can, in turn, be hydrolyzed to 3,3-spirocyclic oxindoles.

引用

页码：1869 / 1871

页数：3

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