Synthesis and antimicrobial activity of novel arylideneisothiosemicarbazones

被引：20

作者：

Cardia, MC

Begala, M

Delogu, A

Maccioni, E

Plumitallo, A

机构：

[1] Univ Cagliari, Dipartimento Farmaco Chim Tecnol, I-09124 Cagliari, Italy

[2] Univ Cagliari, Dipartimento Sci Chirurg & Trapianti Organo, Sez Microbiol & Virol, I-09100 Cagliari, Italy

来源：

FARMACO | 2000年 / 55卷 / 02期

关键词：

arylideneisothiosemicarbazones; antimicrobial; structure-activity relationships;

D O I：

10.1016/S0014-827X(99)00124-X

中图分类号：

R9 [药学];

学科分类号：

1007 [药学];

摘要：

Arylidenimidazoles bearing a thioethereal function in the position 2 of the imidazole ring show good antimicrobial activity. We now report on the synthesis and the biological properties of some novel arylidenisothiosemicarbazones, structurally related to the arylideneiminoimidazoles of which they can be considerecd the linear precursors. Particular attention has been put on the influence of structural modifications on the biological activity. (C) 2000 Elsevier Science S.A. All rights reserved.

引用

页码：93 / 98

页数：6

共 13 条

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NEUE SCHWEFEL-HALTIGE CHEMOTHERAPEUTIKA [J].