Combination of staphylococcal chromosome cassette SCCmec type V and Panton-Valentine leukocidin genes in a methicillin-resistant Staphylococcus aureus that caused necrotizing pneumonia in Greece

被引：22

作者：

Gerogianni, Irini

Mpatavanis, Georgios

Gourgoulianis, Konstantinos

Maniatis, Antonios

Spiliopoulou, Iris

Petinaki, Efi ^{[1
]}

机构：

[1] Univ Larissa, Sch Med, Dept Microbiol, Larisa 41110, Greece

[2] Univ Hosp Larissa, Dept Resp Med, Larisa 41110, Greece

[3] Univ Patras, Dept Microbiol, Sch Med, Patras, Greece

来源：

DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE | 2006年 / 56卷 / 02期

关键词：

necrotizing pneumonia; PVL; CA-MRSA; SCCmec type V;

D O I：

10.1016/j.diagmicrobio.2006.06.005

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

We describe a case of necrotizing pneumonia in Greece caused by a community-acquired methicillin-resistant Staphylococcus aureus (MRSA) producing Panton-Valentine leukocidin (PVL) carrying the staphylococcal chromosome cassette mec (SCCmec) type V The pulse field gel electrophoresis (PFGE) pattern of this strain differed significantly from the PVL-positive multi-locus sequence typing (MLST)-80 clone of MRSA, which predominates in Greece and in Europe. Further analysis of this strain revealed that it belonged to the agr1 allele type, and its resistance to tobramycin, gentamicin, and kanamycin was associated to the presence of aac-(6')-Ie+aph(2') gene. This is the 1st report that documents the emergence of CA-MRSA with PVL genes in combination with the SCCmec type V in Europe. (c) 2006 Elsevier Inc. All rights reserved.

引用

页码：213 / 216

页数：4

共 17 条

[1]

[Anonymous], 2000, M2A7 NCCLS

[2] Successful multiresistant community-associated methicillin-resistant Staphylococcus aureus lineage from Taipei, Taiwan, that carries either the novel staphylococcal chromosome cassette mec (SCCmec) type VT or SCCmec type IV [J].