Regional reductions of gray matter volume in familial dyslexia

被引:98
作者
Brambati, SM
Termine, C
Ruffino, M
Stella, G
Fazio, F
Cappa, SF
Perani, D
机构
[1] Vita Salute H San Raffaele Univ, IBFM, CNR, I-20132 Milan, Italy
[2] Univ Milano Bicocca, Milan, Italy
[3] Univ Insubria, Varese, Italy
[4] Univ Urbino, Inst Psychol, I-61029 Urbino, Italy
关键词
D O I
10.1212/01.WNL.0000134673.95020.EE
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
An in vivo anatomic study of gray matter volume was performed in a group of familial dyslexic individuals, using an optimized method of voxel-based morphometry. Focal abnormalities in gray matter volume were observed bilaterally in the planum temporale, inferior temporal cortex, and cerebellar nuclei, suggesting that the underlying anatomic abnormalities may be responsible for defective written language acquisition in these subjects.
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页码:742 / 745
页数:4
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