Validation of Chinese version of the Morisky Medication Adherence Scale in patients with epilepsy

被引：76

作者：

Yang, Aifang ^{[1
]}

Wang, Bin ^{[1
]}

Zhu, Guoxing ^{[2
]}

Jiao, Zheng ^{[1
]}

Fang, Youxin ^{[2
]}

Tang, Fengmin ^{[1
]}

Ma, Chunlai ^{[1
]}

Zhao, Yue ^{[1
]}

Cheng, Cai ^{[1
]}

Zhong, Mingkang ^{[1
]}

机构：

[1] Fudan Univ, Dept Pharm, HuaShan Hosp, Shanghai 200040, Peoples R China

[2] Fudan Univ, Dept Neurol, HuaShan Hosp, Shanghai 200040, Peoples R China

来源：

SEIZURE-EUROPEAN JOURNAL OF EPILEPSY | 2014年 / 23卷 / 04期

关键词：

Adherence; Validation; Epilepsy; Scale; ANTIEPILEPTIC DRUGS; PSYCHOMETRIC PROPERTIES; NONADHERENCE; CHILDREN; SEIZURES; ASSOCIATION; PREVALENCE; VALIDITY; BELIEFS; ADULTS;

D O I：

10.1016/j.seizure.2014.01.003

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

100204 [神经病学];

摘要：

Purpose: This study aimed to validate a Chinese version of the Morisky Medication Adherence Scale (MMAS-8) in patients with epilepsy. The relationships between adherence, seizure frequency, and adverse effects were assessed using this method. Methods: Data from patients diagnosed with epilepsy at the Department of Neurology of Huashan Hospital were collected between January and June 2013. To validate the MMAS-8, internal consistency, test-retest reliability, and factor analysis were calculated. Relationships between adherence, seizure frequency, and adverse effects were assessed using Pearson's correlation. Results: One hundred and eleven patients were recruited. The MMAS-8 had moderate internal consistency (Cronbach's alpha = 0.556) and good test-retest reliability (intraclass correlation coefficient = 0.729). The MMAS-8 adherence rate was 79.2%. MMAS-8 adherence was negatively correlated with seizure frequency and adverse effects (r = -0.708, p < 0.001; r = -0.484, p < 0.001). Conclusion: The MMAS-8 scale can be used as a tool to assess medication adherence in Chinese patients with epilepsy. Better seizure control and lower rates of adverse effects were significantly correlated with higher adherence scores. (C) 2014 British Epilepsy Association. Published by Elsevier Ltd. All rights reserved.

引用

页码：295 / 299

页数：5

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