Emerging Human Middle East Respiratory Syndrome Coronavirus Causes Widespread Infection and Alveolar Damage in Human Lungs

被引：86

作者：

Hocke, Andreas C. ^{[1
]}

Becher, Anne ^{[1
]}

Knepper, Jessica ^{[2
]}

Peter, Andrea ^{[1
]}

Holland, Gudrun ^{[2
]}

Toennies, Mario ^{[3
]}

Bauer, Torsten T. ^{[3
]}

Schneider, Paul ^{[4
]}

Neudecker, Jens ^{[5
]}

Muth, Doreen ^{[6
]}

Wendtner, Clemens M. ^{[7
]}

Rueckert, Jens C. ^{[5
]}

Drosten, Christian ^{[6
]}

Gruber, Achim D. ^{[8
]}

Laue, Michael ^{[2
]}

Suttorp, Norbert ^{[1
]}

Hippenstiel, Stefan ^{[1
]}

Wolff, Thorsten

机构：

[1] Charite, D-13353 Berlin, Germany

[2] Robert Koch Inst, Berlin, Germany

[3] Chest Hosp Heckeshorn, Berlin, Germany

[4] DRK Clin, Berlin, Germany

[5] Univ Med Berlin, Charite Campus Mitte, Berlin, Germany

[6] Univ Bonn, Med Ctr, Bonn, Germany

[7] Klinikum Schwabing, Munich, Germany

[8] Free Univ Berlin, Berlin, Germany

来源：

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE | 2013年 / 188卷 / 07期

关键词：

PATHOGENESIS; PNEUMONIA; INJURY; ASSAYS; SARS; EMC;

D O I：

10.1164/rccm.201305-0954LE

中图分类号：

R4 [临床医学];

学科分类号：

1002 ; 100602 ;

摘要：

引用

页码：882 / 886

页数：6

共 20 条

[1] Regulation and Repair of the Alveolar-Capillary Barrier in Acute Lung Injury [J].

Bhattacharya, Jahar ;

Matthay, Michael A. .

ANNUAL REVIEW OF PHYSIOLOGY, VOL 75, 2013, 75 :593-615

[2]

Corman VM, 2012, EUROSURVEILLANCE, V17, P2

[3]

CRAPO JD, 1982, AM REV RESPIR DIS, V126, P332

[4] Occludin: One Protein, Many Forms [J].

Cummins, Philip M. .

MOLECULAR AND CELLULAR BIOLOGY, 2012, 32 (02) :242-250

[5] Clinical features and virological analysis of a case of Middle East respiratory syndrome coronavirus infection [J].

Drosten, Christian ;

Seilmaier, Michael ;

Corman, Victor M. ;

Hartmann, Wulf ;

Scheible, Gregor ;

Sack, Stefan ;

Guggemos, Wolfgang ;

Kallies, Rene ;

Muth, Doreen ;

Junglen, Sandra ;

Muller, Marcel A. ;

Haas, Walter ;

Guberina, Nana ;

Rohnisch, Tim ;

Schmid-Wendtner, Monika ;

Aldabbagh, Souhaib ;

Dittmer, Ulf ;

Gold, Hermann ;

Graf, Petra ;

Bonin, Frank ;

Rambaut, Andrew ;

Wendtner, Clemens-Martin .

LANCET INFECTIOUS DISEASES, 2013, 13 (09) :745-751

[6] Guidelines for the use and interpretation of assays for monitoring cell death in higher eukaryotes [J].

Galluzzi, L. ;

Aaronson, S. A. ;

Abrams, J. ;

Alnemri, E. S. ;

Andrews, D. W. ;

Baehrecke, E. H. ;

Bazan, N. G. ;

Blagosklonny, M. V. ;

Blomgren, K. ;

Borner, C. ;

Bredesen, D. E. ;

Brenner, C. ;

Castedo, M. ;

Cidlowski, J. A. ;

Ciechanover, A. ;

Cohen, G. M. ;

De Laurenzi, V. ;

De Maria, R. ;

Deshmukh, M. ;

Dynlacht, B. D. ;

El-Deiry, W. S. ;

Flavell, R. A. ;

Fulda, S. ;

Garrido, C. ;

Golstein, P. ;

Gougeon, M-L ;

Green, D. R. ;

Gronemeyer, H. ;

Hajnoczky, G. ;

Hardwick, J. M. ;

Hengartner, M. O. ;

Ichijo, H. ;

Jaattela, M. ;

Kepp, O. ;

Kimchi, A. ;

Klionsky, D. J. ;

Knight, R. A. ;

Kornbluth, S. ;

Kumar, S. ;

Levine, B. ;

Lipton, S. A. ;

Lugli, E. ;

Madeo, F. ;

Malorni, W. ;

Marine, J-C W. ;

Martin, S. J. ;

Medema, J. P. ;

Mehlen, P. ;

Melino, G. ;

Moll, U. M. .

CELL DEATH AND DIFFERENTIATION, 2009, 16 (08) :1093-1107

[7] Multiple organ infection and the pathogenesis of SARS [J].

Gu, J ;

Gong, EC ;

Zhang, B ;

Zheng, J ;

Gao, ZF ;

Zhong, YF ;

Zou, WZ ;

Zhan, J ;

Wang, SL ;

Xie, ZG ;

Zhuang, H ;

Wu, BQ ;

Zhong, HH ;

Shao, HQ ;

Fang, WG ;

Gao, DS ;

Pei, F ;

Li, XW ;

He, ZP ;

Xu, DZ ;

Shi, XY ;

Anderson, VM ;

Leong, ASY .

JOURNAL OF EXPERIMENTAL MEDICINE, 2005, 202 (03) :415-424

[8] H5N1 infection of the respiratory tract and beyond: a molecular pathology study [J].

Gu, Jiang ;

Xie, Zhigang ;

Gao, Zhancheng ;

Liu, Jinhua ;

Korteweg, Christine ;

Ye, Juxiang ;

Lau, Lok Ting ;

Lu, Jie ;

Gao, Zifen ;

Zhang, Bo ;

McNutt, Michael A. ;

Lu, Min ;

Anderson, Virginia M. ;

Gong, Encong ;

Yu, Albert Cheung Hoi ;

Lipkin, W. Ian .

LANCET, 2007, 370 (9593) :1137-1145

[9]

Jobe AH, 1998, P ASSOC AM PHYSICIAN, V110, P489

[10] Biology of alveolar type II cells [J].

Mason, RJ .

RESPIROLOGY, 2006, 11 :S12-S15

← 1 2 →