Conjugate addition of diorganozincs to alpha,beta-unsaturated ketones catalyzed by a copper(I)-sulfonamide combined system

被引：92

作者：

Kitamura, M

Miki, T

Nakano, K

Noyori, R

机构：

[1] NAGOYA UNIV,DEPT CHEM,NAGOYA,AICHI 46401,JAPAN

[2] NAGOYA UNIV,MOL CHIRAL RES UNIT,NAGOYA,AICHI 46401,JAPAN

来源：

TETRAHEDRON LETTERS | 1996年 / 37卷 / 29期

关键词：

D O I：

10.1016/0040-4039(96)01038-6

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

In the presence of a Cu(I)-N-monosubstituted sulfonamide combined catalyst system, diorganozincs react with alpha,beta-unsaturated ketones to generate Zn enolates, which may be hydrolyzed, giving the beta-substituted ketones, or used for further aldol reaction or Pd(O)-catalyzed reaction with allyl acetate leading to the regiospecific alpha,beta-vicinal condensation products. Copyright (C) 1996 Elsevier Science Ltd

引用

页码：5141 / 5144

页数：4

共 33 条

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