Synthesis of thio- and oxo-analogues of isopsoralen

被引：25

作者：

Clarke, DJ ^{[1
]}

Robinson, RS ^{[1
]}

机构：

[1] Univ KwaZulu Natal, Sch Chem & Phys Sci, Warren Res Lab, ZA-3209 Pietermaritzburg, South Africa

来源：

TETRAHEDRON | 2002年 / 58卷 / 14期

基金：

新加坡国家研究基金会;

关键词：

benzopyrans; rearrangements; ozonolysis;

D O I：

10.1016/S0040-4020(02)00161-8

中图分类号：

O62 [有机化学];

学科分类号：

070303 [有机化学]; 081704 [应用化学];

摘要：

A range of novel 5'-substituted 7-oxo and 7-thioisopsoralens were synthesized via a Claisen rearranged allyl aryl ether followed by reductive ozonolysis in the presence of a suitable solvent. In some cases dimethylthiocarbamoyl chloride was used as a protecting group and to introduce the thiol moiety. (C) 2002 Elsevier Science Ltd. All rights reserved.

引用

页码：2831 / 2837

页数：7

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