Pharmacogenetics: ethical problems and solutions

被引:25
作者
Breckenridge, A
Lindpaintner, K
Lipton, P
McLeod, H
Rothstein, M
Wallace, H
机构
[1] Hoffmann La Roche Ag, Res, Grenzach, Germany
[2] Hoffmann La Roche Ag, Roche Genet, Grenzach, Germany
[3] Hoffmann La Roche Ag, Roche Ctr Med Genom, Grenzach, Germany
[4] Univ Cambridge, Cambridge CB2 1TN, England
[5] Washington Univ, Sch Med, St Louis, MO 63130 USA
[6] Univ Louisville, Sch Med, Inst Bioeth Hlth Policy & Law, Louisville, KY 40292 USA
关键词
D O I
10.1038/nrg1431
中图分类号
Q3 [遗传学];
学科分类号
071007 ; 090102 ;
摘要
Regulators, drug companies, academic scientists, bioethicists, clinicians and, increasingly, the general public are starting to realize that pharmacogenetics (PGx) will probably have a huge impact on the way in which we treat both common and rare diseases. But how much thought has gone into the ethical issues that the incorportation of phamacogenetic testing into drug discovery, prescription and use will entail? It seems that "quite a bit" is the answer, as the diverse viewpoints of representatives of all of these groups presented here illustrate. However, these views also highlight that now is the time to start formulating and implementing solutions to these potential problems.
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页码:676 / 680
页数:6
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