Synthesis and biological activity of novel 4-/5-/6-/7-nitro-N′-(4-aryl-1,3-thiazol-2-yl)-1H-indole-2-carbohydrazide derivatives

被引：5

作者：

Ashalatha, B. V.

Narayana, B. ^{[1
]}

Kumari, N. Suchetha

机构：

[1] Mangalore Univ, Dept Postgrad Studies & Res Chem, Mangalagangothri 574199, India

[2] KS Hegde Med Acad, Dept Biochem, Deralakatte, India

来源：

PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS | 2006年 / 181卷 / 12期

关键词：

1H-indole; 1,3-thiazole; biological activity; nitro; synthesis;

D O I：

10.1080/10426500600864684

中图分类号：

O61 [无机化学];

学科分类号：

070301 [无机化学]; 081704 [应用化学];

摘要：

New 4-/5-/6-/7-nitro-N'-(4-aryl-1,3-thiazol-2-yl)-1H-indole-2-carbohydrazides (4a-t) were prepared by treating respective nitroindole thiosemicarbazide with aromatic acylbromides. The newly synthesized compounds were characterized by analytical and spectral data. The compounds were also screened for antifungal and antibacterial activity. Some of the compounds exhibited promising antimicrobial activity.

引用

页码：2785 / 2795

页数：11

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