Cell instructive polymers

被引:29
作者
Matsumoto, Takuya [1 ]
Mooney, David J. [1 ]
机构
[1] Harvard Univ, Div Engn & Appl Sci, Cambridge, MA 02138 USA
来源
TISSUE ENGINEERING I: SCAFFOLD SYSTEMS FOR TISSUE ENGINEERING | 2006年 / 102卷
关键词
cells; external stimuli; growth factors; synthetic extracellular matrix;
D O I
10.1007/b137207
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
Polymeric materials used in tissue engineering were initially used solely as delivery vehicles for transplanting cells. However, these materials are currently designed to actively regulate the resultant tissue structure and function. This control is achieved through spatial and temporal regulation of various cues (e.g., adhesion ligands, growth factors) provided to interacting cells from the material. These polymeric materials that control cell function and tissue formation are termed cell instructive polymers, and recent trends in their design are outlined in this chapter.
引用
收藏
页码:113 / 137
页数:25
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