One-pot synthesis of functionalized asymmetric 5,10,15,20-substituted porphyrins from 5,15-diaryl-or -dialkyl-porphyrins

被引：44

作者：

Feng, XD ^{[1
]}

Senge, MO ^{[1
]}

机构：

[1] Free Univ Berlin, Inst Chem Organ Chem, D-14195 Berlin, Germany

来源：

TETRAHEDRON | 2000年 / 56卷 / 04期

关键词：

porphyrins and analogues; lithium and compounds; substitution; alkyl halides;

D O I：

10.1016/S0040-4020(99)01055-8

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Reaction of easily available (5,15-dialkyl/arylporphyrinato)nickel(II) with RLi under anhydrous conditions affords 5,10,15-trisubstituted porphyrin anions that can be used as in situ nucleophiles for reaction with alkyl iodide reagents. After oxidation with atmospheric oxygen, 5,10,15,20-tetrasubstituted porphyrins are obtained in good yields. This method permits introduction of all base-stable functional groups into the meso position of porphyrins. (C) 2000 Elsevier Science Ltd. All rights reserved.

引用

页码：587 / 590

页数：4

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