Use of (S)-N-tert-butoxycarbonylaziridine-2-carboxylate derivatives for alpha-amino acid synthesis

被引：67

作者：

Baldwin, JE ^{[1
]}

Farthing, CN ^{[1
]}

Russell, AT ^{[1
]}

Schofield, CJ ^{[1
]}

Spivey, AC ^{[1
]}

机构：

[1] OXFORD CTR MOLEC SCI, OXFORD OX1 3QY, ENGLAND

来源：

TETRAHEDRON LETTERS | 1996年 / 37卷 / 21期

关键词：

D O I：

10.1016/0040-4039(96)00676-4

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

(S)tert-Butyl-N-tert-butoxycarbonylaziridine-2-carboxylate and (S)-tert-butyl-N-tert-butoxycarbonylaziridine-2-carboxamide were synthesised and found to react with copper 'catalysed' Grignard reagents to give protected alpha-amino acids in moderate to good yields. Copyright (C) 1996 Elsevier Science Ltd

引用

页码：3761 / 3764

页数：4

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