Mood stabilizer augmentation with olanzapine in acutely manic children

被引：48

作者：

Chang, KD ^{[1
]}

Ketter, TA ^{[1
]}

机构：

[1] Stanford Univ, Sch Med, Dept Psychiat & Behav Sci, Stanford, CA USA

来源：

JOURNAL OF CHILD AND ADOLESCENT PSYCHOPHARMACOLOGY | 2000年 / 10卷 / 01期

关键词：

D O I：

10.1089/cap.2000.10.45

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

We report on three cases of acutely manic prepubertal children diagnosed with bipolar disorder who were treated with olanzapine in addition to their existing mood stabilizer regimens. All three had marked improvement of their manic symptoms within 3-5 days of beginning olanzapine therapy as measured by clinician-rated instruments. Adverse effects included sedation and weight gain. These results suggest that olanzapine may have an antimanic or mood stabilizing effect in acutely manic children with bipolar disorder.

引用

页码：45 / 49

页数：5

共 17 条

[1] CLONAZEPAM IN CHILDHOOD ANXIETY DISORDERS [J].

GRAAE, F ;

MILNER, J ;

RIZZOTTO, L ;

KLEIN, RG .

JOURNAL OF THE AMERICAN ACADEMY OF CHILD AND ADOLESCENT PSYCHIATRY, 1994, 33 (03) :372-376

[2]

John V, 1998, CAN J PSYCHIAT, V43, P1054

[3]

KASPER S, 1992, Encephale, V18, P45

[4] Rapid efficacy of olanzapine augmentation in nonpsychotic bipolar mixed states [J].

Ketter, TA ;

Winsberg, ME ;

DeGolia, SG ;

Dunai, M ;

Tate, DL ;

Strong, CM .

JOURNAL OF CLINICAL PSYCHIATRY, 1998, 59 (02) :83-85

[5] Open-label olanzapine treatment in five preadolescent children [J].

Krishnamoorthy, J ;

King, BH .

JOURNAL OF CHILD AND ADOLESCENT PSYCHOPHARMACOLOGY, 1998, 8 (02) :107-113

[6] Childhood-onset schizophrenia: An open-label study of olanzapine in adolescents [J].

Kumra, S ;

Jacobsen, LK ;

Lenane, M ;

Karp, BI ;

Frazier, JA ;

Smith, AK ;

Bedwell, J ;

Lee, P ;

Malanga, CJ ;

Hamburger, S ;

Rapoport, JI .

JOURNAL OF THE AMERICAN ACADEMY OF CHILD AND ADOLESCENT PSYCHIATRY, 1998, 37 (04) :377-385

[7] Olanzapine-induced manic-like syndrome [J].

Lindenmayer, JP ;

Klebanov, R .

JOURNAL OF CLINICAL PSYCHIATRY, 1998, 59 (06) :318-319

[8] Mania associated with olanzapine [J].

London, JA .

JOURNAL OF THE AMERICAN ACADEMY OF CHILD AND ADOLESCENT PSYCHIATRY, 1998, 37 (02) :135-136

[9] Olanzapine in treatment-resistant bipolar disorder [J].

McElroy, SL ;

Frye, M ;

Denicoff, K ;

Altshuler, L ;

Nolen, W ;

Kupka, R ;

Suppes, T ;

Keck, PE ;

Leverich, GS ;

Kmetz, GF ;

Post, RM .

JOURNAL OF AFFECTIVE DISORDERS, 1998, 49 (02) :119-122

[10]

NOWLINFINCH NL, 1994, J CLIN PSYCHIAT, V55, P26

← 1 2 →