Stability change of DNA-carrying colloidal particle induced by hybridization with target DNA

被引：45

作者：

Mori, T

Maeda, M

机构：

[1] RIKEN, Inst Phys & Chem Res, Wako, Saitama 3510198, Japan

[2] Kyushu Univ, Grad Sch Engn, Dept Appl Chem, Higashi Ku, Fukuoka 8128581, Japan

来源：

POLYMER JOURNAL | 2002年 / 34卷 / 08期

基金：

日本学术振兴会;

关键词：

aggregation; colloid; salt effect; DNA; poly(N-isopropylacrylamide);

D O I：

10.1295/polymj.34.624

中图分类号：

O63 [高分子化学（高聚物）];

学科分类号：

070305 ; 080501 ; 081704 ;

摘要：

A novel aggregation mechanism of DNA-containing colloidal particle based on the stability decrease of colloidal particle accompanied by the duplex formation of the surface DNA with the complementary DNA is proposed. Using the particle aggregation assay according to the present mechanism, the sequence- and the chain length-selective DNA detection is attained.

引用

收藏

页码：624 / 628

页数：5

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