Ultrafast charge transfer and solvation of DNA minor groove binder: Hoechst 33258 in restricted environments

被引：35

作者：

Banerjee, Debapriya ^{[1
]}

Pal, Samir Kumar ^{[1
]}

机构：

[1] SN Bose Natl Ctr Basic Sci, Dept Chem Biol & Macromol Sci, Unitd Nano Sci & Technol, Kolkata 700098, India

来源：

CHEMICAL PHYSICS LETTERS | 2006年 / 432卷 / 1-3期

关键词：

DYNAMICS; BINDING; MICELLE; COMPLEX; RECOGNITION; CHROMOSOMES; SURFACE; WATER; DYES;

D O I：

10.1016/j.cplett.2006.10.018

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

Picosecond resolved photophysical studies on a DNA minor groove binder, H33258 in bulk buffer and various restricted media including DNA reveal excited state charge transfer as an important mode of excited state relaxation. The charge transfer is found to be essentially associated with intramolecular twisting of the probe, being absent in SDS micellar environment and in DNA where twisting is hindered. Solvation and rotational dynamics of the probe in various restricted media including DNA are explored. A significantly longer component (8.5 ns) in DNA-solvation dynamics, which is well known to be associated with delta-relaxation of the DNA, is identified. (c) 2006 Elsevier B.V. All rights reserved.

引用

页码：257 / 262

页数：6

共 35 条

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Adhikary A., 1997, Radioprotection, V32, P89

[2] On the protonation equilibrium for the benzimidazole derivative Hoechst 33258:: An electronic molecular orbital study [J].