Statistical Considerations in Meta-analysis

被引：22

作者：

Barza, Michael ^{[2
,3
]}

Trikalinos, Thomas A. ^{[1
,3
]}

Lau, Joseph ^{[1
,3
]}

机构：

[1] Tufts Med Ctr, Inst Clin Res & Hlth Policy Studies, Ctr Clin Evidence Synth, Boston, MA 02111 USA

[2] Caritas Carney Hosp, Dept Med, Boston, MA USA

[3] Tufts Univ, Sch Med, Boston, MA 02111 USA

来源：

INFECTIOUS DISEASE CLINICS OF NORTH AMERICA | 2009年 / 23卷 / 02期

关键词：

Systematic review; Meta-analysis; Meta-regression; Quantitative synthesis; Pooling; DIAGNOSTIC-TEST ACCURACY; INDIVIDUAL PATIENT DATA; CLINICAL-TRIALS; SYSTEMATIC REVIEWS; MYOCARDIAL-INFARCTION; RANDOMIZED-TRIALS; UNDERLYING RISK; HETEROGENEITY; QUALITY; ASSOCIATIONS;

D O I：

10.1016/j.idc.2009.01.003

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Systematic reviews and meta-analyses have recently emerged as key sources of evidence to inform clinical care, from bedside individualized decisions to policy making. This article discusses the principles behind statistical methods for quantitative evidence synthesis, including meta-analysis and meta-regression. The authors present pertinent concepts in an intuitive and nonmathernatical fashion by use of examples from the infectious diseases literature.

引用

页码：195 / +

页数：17

共 63 条

[1] Meta-analysis, Simpson's paradox, and the number needed to treat [J].

Altman D.G. ;

Deeks J.J. .

BMC Medical Research Methodology, 2 (1) :1-5

[2]

[Anonymous], 1976, Edu Res, DOI [10.3102/0013189x005010003, DOI 10.2307/1174772, 10.2307/1174772ISSN0536-1036, DOI 10.3102/0013189X005010003, 10.3102/0013189X005010003]

[3]

Arends L, 2006, MULTIVARIATE METAANA

[4] Reading and critically appraising systematic reviews and meta-analyses: A short primer with a focus on hepatology [J].

Balk, EM ;

Lau, J ;

Bonis, PAL .

JOURNAL OF HEPATOLOGY, 2005, 43 (04) :729-736

[5] Individual patient- versus group-level data meta-regressions for the investigation of treatment effect modifiers: ecological bias rears its ugly head [J].

Berlin, JA ;

Santanna, J ;

Schmid, CH ;

Szczech, LA ;

Feldman, HI .

STATISTICS IN MEDICINE, 2002, 21 (03) :371-387

[6] EVIDENCE FAVORING USE OF ANTICOAGULANTS IN HOSPITAL PHASE OF ACUTE MYOCARDIAL-INFARCTION [J].

CHALMERS, TC ;

MATTA, RJ ;

SMITH, H ;

KUNZLER, AM .

NEW ENGLAND JOURNAL OF MEDICINE, 1977, 297 (20) :1091-1096

[7] THE COMBINATION OF ESTIMATES FROM DIFFERENT EXPERIMENTS [J].

COCHRAN, WG .

BIOMETRICS, 1954, 10 (01) :101-129

[8] Formulating questions and locating primary studies for inclusion in systematic reviews [J].

Counsell, C .

ANNALS OF INTERNAL MEDICINE, 1997, 127 (05) :380-387

[9] METAANALYSIS IN CLINICAL-TRIALS [J].

DERSIMONIAN, R ;

LAIRD, N .

CONTROLLED CLINICAL TRIALS, 1986, 7 (03) :177-188

[10] Evaluation of underlying risk as a source of heterogeneity in meta-analyses: A simulation study of Bayesian and frequentist implementations of three models [J].

Dohoo, Ian ;

Stryhn, Henrik ;

Sanchez, Javier .

PREVENTIVE VETERINARY MEDICINE, 2007, 81 (1-3) :38-55

← 1 2 3 4 5 6 7 →