Synthesis of novel palladacycles and their application in Heck and Suzuki reactions under aerobic conditions

被引：121

作者：

Xiong, ZC

Wang, ND

Dai, MJ

Li, A

Chen, JH

Yang, Z ^{[1
]}

机构：

[1] Coll Chem, Key Lab Bioorgan Chem & Mol Engn, Minist Educ, Beijing 100871, Peoples R China

[2] Peking Univ, Lab Chem Genet, Shenzhen Grad Sch, Shenzhen 518055, Peoples R China

[3] VivoQuest Inc, Valley Cottage, NY 10989 USA

来源：

ORGANIC LETTERS | 2004年 / 6卷 / 19期

关键词：

D O I：

10.1021/ol048749s

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Design and synthesis of a novel family of furancarbothioamide-based palladacycles are reported herein. These palladacycles are thermally stable, not sensitive to air or moisture, and are applied effectively in the Heck reaction of aryl halides with terminal olefins and in the Suzuki reaction of aryl halides with arylboronic acids. These reactions were performed under aerobic conditions, leading to turnover numbers (TONs) up to 1 x 10(5).

引用

收藏

页码：3337 / 3340

页数：4

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