When are research risks reasonable in relation to anticipated benefits?

被引：117

作者：

Weijer, C ^{[1
]}

Miller, PB ^{[1
]}

机构：

[1] Dalhousie Univ, Dept Bioeth, Halifax, NS B3H 4H7, Canada

来源：

NATURE MEDICINE | 2004年 / 10卷 / 06期

基金：

加拿大健康研究院;

关键词：

D O I：

10.1038/nm0604-570

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The question "When are research risks reasonable in relation to anticipated benefits?" is at the heart of disputes in the ethics of clinical research. Institutional review boards are often criticized for inconsistent decision-making, a problem that is compounded by a number of contemporary controversies, including the ethics of research involving placebo controls, developing countries, incapable adults and emergency rooms. If this pressing ethical question is to be addressed in a principled way, then a systematic approach to the ethics of risk in research is required. Component analysis provides such a systematic approach.

引用

页码：570 / 573

页数：4

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