Cellular aspects of wound healing

被引:94
作者
de Mendonca, Ricardo Jose [1 ]
Coutinho-Netto, Joaquim [1 ]
机构
[1] Univ Sao Paulo, Fac Med Ribeirao Preto, Dept Bioquim & Imunol, BR-14040900 Ribeirao Preto, SP, Brazil
关键词
Angiogenesis inducing agents; Capillary permeability; Wound healing; VASCULAR-PERMEABILITY FACTOR; ENDOTHELIAL GROWTH-FACTOR; GRANULATION-TISSUE; FACTOR BB; ANGIOGENESIS; REPAIR; EXTRAVASATION; MECHANISMS; EXPRESSION; THERAPY;
D O I
10.1590/S0365-05962009000300007
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100227 [皮肤病学];
摘要
Wound healing is a dynamic interactive process that involves a sequence of molecular and cellular events. Recent advances in cellular and molecular biology have greatly expanded our understanding of the biological process involved in wound repair and tissue regeneration. From plasma extravasation, with coagulation and platelet aggregation, to reepithelialization and remodeling of injured tissue, the organism acts by trying to restore functionality tissue. Thus, the present study encompasses several cellular aspects involved in the wound healing process, as well as the main drugs used in treating the pathology related to wound healing complications. Economic aspects are also addressed, mainly related to chronic wounds of diabetic feet.
引用
收藏
页码:257 / 262
页数:6
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