The synthesis of imidazoline analogs of the Kainoid family

被引:8
作者
Baumgartner, H [1 ]
OSullivan, AC [1 ]
机构
[1] CIBA GEIGY AG,CH-4002 BASEL,SWITZERLAND
关键词
D O I
10.1016/S0040-4020(97)00005-7
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
In an effort to mimic the anthelmintic and insecticidal activties of kainic 1 and domoic 2 acids with compounds of simpler structure and much easier accessibility, the highly functionalised imidazolines 4, 27, and 28 were prepared. This involved a synthesis of suitably protected beta-aminoglutamic acid derivatives as key intermediates, which were condensed with orthoesters and deprotected to yield the desired compounds. (C) 1997 Elsevier Science Ltd.
引用
收藏
页码:2775 / 2784
页数:10
相关论文
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