Plasma homocysteine concentrations in type II diabetic patients in India: Relationship to body weight

被引:17
作者
Das, S [1 ]
Reynolds, T [1 ]
Patnaik, A [1 ]
Rais, N [1 ]
Fink, LM [1 ]
Fonseca, VA [1 ]
机构
[1] SCB Med Coll & Hosp, Cuttack, Orissa, India
关键词
D O I
10.1016/S1056-8727(99)00045-8
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Hyperhomocysteinemia has been established as a risk factor for cardiovascular disease and occurs with a high prevalence in patients with type II diabetes and microvascular disease. In order to determine whether plasma homocysteine concentrations vary with body-mass index in patients with type II diabetes, we measured plasma homocysteine in lean, normal weight, and overweight subjects living in India. Plasma homocysteine concentrations were significantly lower in the lean persons with diabetes when compared to those who were obese and compared to control subjects (p < 0.02). We conclude that plasma homocysteine concentrations are lower in lean persons with type II diabetes and that this efficiency in homocysteine metabolism may contribute towards protection from cardiovascular disease in this population (Journal of Diabetes and Its Complications 13;4:200-203, 1999.) (C) 1999 Elsevier Science Inc.
引用
收藏
页码:200 / 203
页数:4
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