A monoclinic polymorph of venlafaxine hydrochloride

被引：16

作者：

Sivalakshmidevi, A

Vyas, K

Rao, SM

Reddy, GO

机构：

[1] Dr Reddys Labs, Discovery Res, Hyderabad 500016, Andhra Pradesh, India

[2] Dr Reddys Labs, Custom Chem Serv, Hyderabad 500016, Andhra Pradesh, India

来源：

ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE | 2002年 / 58卷

关键词：

D O I：

10.1107/S160053680201588X

中图分类号：

O7 [晶体学];

学科分类号：

0702 ; 070205 ; 0703 ; 080501 ;

摘要：

Venlafaxine hydrochloride, [(+/-)-N,N-dimethyl-2-(1-hydroxycyclohex-1-yl)-2-(4-methoxyphenyl) ethylamine hydrochloride, C17H28ClNO2] is found to crystallize in both orthorhombic and monoclinic crystal systems. The molecular structures in the two polymorphs differ in the conformations of the substituents at the ethylamine group. In the monoclinic crystal structure, the molecules translated along the a axis are linked by Cl- ions through O-H...Cl and N-H...Cl hydrogen bonds to form infinite one-dimensional chains.

引用

页码：O1072 / O1074

页数：3

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