Linkage disequilibrium and recombination in hominid mitochondrial DNA

被引：203

作者：

Awadalla, P

Eyre-Walker, A ^{[1
]}

Smith, JM

机构：

[1] Univ Sussex, Ctr Study Evolut, Brighton BN1 9QG, E Sussex, England

[2] Univ Sussex, Sch Biol Sci, Brighton BN1 9QG, E Sussex, England

[3] Univ Edinburgh, Inst Cell Anim & Populat Biol, Edinburgh EH9 1JT, Midlothian, Scotland

来源：

SCIENCE | 1999年 / 286卷 / 5449期

关键词：

D O I：

10.1126/science.286.5449.2524

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

The assumption that human mitochondrial DNA is inherited from one parent only and therefore does not recombine is questionable, Linkage disequilibrium in human and chimpanzee mitochondrial DNA declines as a function of the distance between sites, This pattern can be attributed to one mechanism only: recombination.

引用

页码：2524 / 2525

页数：2

共 42 条

[1] ANDREWS RM, IN PRESS NATURE GENE
[2] Misconceptions about mitochondria and mammalian fertilization: Implications for theories on human evolution
AnkelSimons, F
Cummins, JM
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1996, 93 (24) : 13859 - 13863
[3] Awadalla P, 1999, GENETICS, V152, P413
[4] LEBER HEREDITARY OPTIC NEUROPATHY - A MODEL FOR MITOCHONDRIAL NEURODEGENERATIVE DISEASES
BROWN, MD
VOLJAVEC, AS
LOTT, MT
MACDONALD, I
WALLACE, DC
[J]. FASEB JOURNAL, 1992, 6 (10) : 2791 - 2799
[5] BROWN MD, 1992, GENETICS, V130, P163
[6] MITOCHONDRIAL-DNA AND HUMAN-EVOLUTION
CANN, RL
STONEKING, M
WILSON, AC
[J]. NATURE, 1987, 325 (6099) : 31 - 36
[7] High recombination rate in natural populations of Plasmodium falciparum
Conway, DJ
Roper, C
Oduola, AMJ
Arnot, DE
Kremsner, PG
Grobusch, MP
Curtis, CF
Greenwood, BM
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1999, 96 (08) : 4506 - 4511
[8] Substitution rate variation among sites in mitochondrial hypervariable region I of humans and chimpanzees
Excoffier, L
Yang, ZH
[J]. MOLECULAR BIOLOGY AND EVOLUTION, 1999, 16 (10) : 1357 - 1368
[9] Reply to Macaulay et al.: (1999):: mitochondrial DNA recombination -: reasons to panic
Eyre-Walker, A
Smith, NH
Smith, JM
[J]. PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES, 1999, 266 (1433) : 2041 - 2042
[10] How clonal are human mitochondria?
Eyre-Walker, A
Smith, NH
Smith, JM
[J]. PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES, 1999, 266 (1418) : 477 - 483

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