Synthesis and absolute configuration of a new 3,4-dihydro-β-carboline-type alkaloid, 3,4-dehydro-5(S)-5-carboxystrictosidine, isolated from Peruvian Una de Gato (Uncaria tomentosa)

被引:14
作者
Kitajima, M [1 ]
Yokoya, M [1 ]
Takayama, H [1 ]
Aimi, N [1 ]
机构
[1] Chiba Univ, Grad Sch Pharmaceut Sci, Inage Ku, Chiba 2638522, Japan
关键词
alkaloid; 3,4-dihydro-beta-carboline; Uncaria;
D O I
10.1248/cpb.50.1376
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
The structure including the absolute configuration of a new glucoalkaloid, 3,4-dehydro-5(S)-5-carboxystrictosidine, isolated from Peruvian U (n) over tildea de Gato (Cat's Claw, original plant: Uncaria tomentosa), was confirmed by synthesis starting from secologanin and L-tryptophan.
引用
收藏
页码:1376 / 1378
页数:3
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LETELIER B, 1988, J HETEROCYCLIC CHEM, V25, P1265