Persistent bacterial infections: The interface of the pathogen and the host immune system

被引：401

作者：

Monack, DM ^{[1
]}

Mueller, A ^{[1
]}

Falkow, S ^{[1
]}

机构：

[1] Stanford Univ, Sch Med, Dept Microbiol & Immunol, Stanford, CA 94305 USA

来源：

NATURE REVIEWS MICROBIOLOGY | 2004年 / 2卷 / 09期

关键词：

D O I：

10.1038/nrmicro955

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Persistent bacterial infections involving Mycobacterium tuberculosis, Salmonella enterica serovar Typhi (S. typhi) and Helicobacter pylori pose significant public-health problems. Multidrug-resistant strains of M. tuberculosis and S. typhi are on the increase, and M. tuberculosis and S. typhi infections are often associated with HIV infection. This review discusses the strategies used by these bacteria during persistent infections that allow them to colonize specific sites in the host and evade immune surveillance. The nature of the host immune response to this type of infection and the balance between clearance of the pathogen and avoidance of damage to host tissues are also discussed.

引用

页码：747 / 765

页数：19

共 250 条

[1] Recombination and clonal groupings within Helicobacter pylori from different geographical regions [J].

Achtman, M ;

Azuma, T ;

Berg, DE ;

Ito, Y ;

Morelli, G ;

Pan, ZJ ;

Suerbaum, S ;

Thompson, SA ;

van der Ende, A ;

van Doorn, LJ .

MOLECULAR MICROBIOLOGY, 1999, 32 (03) :459-470

[2]

ADAMS DO, 1976, AM J PATHOL, V84, P164

[3] PCR-BASED RFLP ANALYSIS OF DNA-SEQUENCE DIVERSITY IN THE GASTRIC PATHOGEN HELICOBACTER-PYLORI [J].

AKOPYANZ, N ;

BUKANOV, N ;

WESTBLOM, TU ;

BERG, DE .

NUCLEIC ACIDS RESEARCH, 1992, 20 (23) :6221-6225

[4] Virulent strains of Helicobacter pylori demonstrate delayed phagocytosis and stimulate homotypic phagosome fusion in macrophages [J].

Allen, LAH ;

Schlesinger, LS ;

Kang, B .

JOURNAL OF EXPERIMENTAL MEDICINE, 2000, 191 (01) :115-127

[5] Disruption of the epithelial apical-junctional complex by Helicobacter pylori CagA [J].

Amieva, MR ;

Vogelmann, R ;

Covacci, A ;

Tompkins, LS ;

Nelson, WJ ;

Falkow, S .

SCIENCE, 2003, 300 (5624) :1430-1434

[6] Helicobacter pylori enter and survive within multivesicular vacuoles of epithelial cells [J].

Amieva, MR ;

Salama, NR ;

Tompkins, LS ;

Falkow, S .

CELLULAR MICROBIOLOGY, 2002, 4 (10) :677-690

[7] A Study of Their Disease Producing Potentialities. Over a Series of Years as Indicated by a Study of Cases [J].

Anderson, Gaylord W. ;

Hamblen, Angeline D. ;

Smith, Helen M. .

AMERICAN JOURNAL OF PUBLIC HEALTH AND THE NATIONS HEALTH, 1936, 26 (04) :396-405

[8] Why Helicobacter pylori has Lewis antigens [J].

Appelmelk, BJ ;

Monteiro, MA ;

Martin, SL ;

Moran, AP ;

Vandenbrouck-Grauls, CMJE .

TRENDS IN MICROBIOLOGY, 2000, 8 (12) :565-570

[9] Density of Helicobacter pylori infection in vivo as assessed by quantitative culture and histology [J].

Atherton, JC ;

Tham, KT ;

Peek, RM ;

Cover, TL ;

Blaser, MJ .

JOURNAL OF INFECTIOUS DISEASES, 1996, 174 (03) :552-556

[10] PATHOGENESIS OF TUBERCULOSIS - PATHWAY TO APICAL LOCALIZATION [J].

BALASUBRAMANIAN, V ;

WIEGESHAUS, EH ;

TAYLOR, BT ;

SMITH, DW .

TUBERCLE AND LUNG DISEASE, 1994, 75 (03) :168-178

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