Aβ-related cerebral amyloid angiopathy

被引:9
作者
Bugiani, O [1 ]
机构
[1] Ist Nazl Neurol Carlo Besta, Milan, Italy
关键词
cerebral amyloid angiopathy; Alzheimer's disease; hereditary cerebral hemorrhage with amyloidosis brain aging;
D O I
10.1007/s10072-004-0204-9
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Cerebral amyloid angiopathy is due to beta-protein accumulation in the vessel walls and occurs in normal aging, Alzheimer's disease and hereditary cerebral hemorrhage with amyloidosis. It causes intraparenchimal and subarachnoid bleeding with hemosiderin deposits and multiple infarcts presenting with headache, stroke and epilepsy. Such lesions may contribute to cognitive impairment. So far, no therapy is available. In future, amyloid in the vessel wall might be addressed by amyloid disaggregating drugs and amyloid antibodies.
引用
收藏
页码:S1 / S2
页数:2
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