Optical coherence angiography

被引:503
作者
Makita, Shuichi [1 ]
Hong, Youngjoo [1 ]
Yamanari, Masahiro [1 ]
Yatagai, Toyohiko [1 ]
Yasuno, Yoshiaki [1 ]
机构
[1] Univ Tsukuba, Inst Appl Phys, Tsukuba, Ibaraki 3058573, Japan
来源
OPTICS EXPRESS | 2006年 / 14卷 / 17期
关键词
RETINAL BLOOD-FLOW; LASER DOPPLER MEASUREMENTS; ULTRA-HIGH-SPEED; REAL-TIME; DYNAMIC-RANGE; TOMOGRAPHY IMAGES; HUMAN SKIN; VELOCITY; NERVE; VESSELS;
D O I
10.1364/OE.14.007821
中图分类号
O43 [光学];
学科分类号
070207 ; 0803 ;
摘要
Noninvasive angiography is demonstrated for the in vivo human eye. Three-dimensional flow imaging has been performed with high-speed spectral-domain optical coherence tomography. Sample motion is compensated by two algorithms. Axial motion between adjacent A-lines within one OCT image is compensated by the Doppler shift due to bulk sample motion. Axial displacements between neighboring images are compensated by a correlation-based algorithm. Three-dimensional vasculature of ocular vessels has been visualized. By integrating volume sets of flow images, two-dimensional images of blood vessels are obtained. Retinal and choroidal blood vessel images are simultaneously obtained by separating the volume set into retinal part and choroidal parts. These are corresponding to fluorescein angiogram and indocyanine angiogram. (c) 2006 Optical Society of America.
引用
收藏
页码:7821 / 7840
页数:20
相关论文
共 48 条
[1]  
[Anonymous], 1992, Multivariate density estimation: theory, practice and visualisation, DOI DOI 10.1002/9780470316849
[2]  
[Anonymous], 2007, Z13612000 ANSI LAS I
[3]  
[Anonymous], 1997, STEREOSCOPIC ATLAS M
[4]  
Atchison D. A., 2000, OPTICS HUMAN EYE
[5]   Three-dimensional reconstruction of blood vessels from in vivo color Doppler optical coherence tomography images [J].
Barton, JK ;
Izatt, JA ;
Kulkarni, MD ;
Yazdanfar, S ;
Welch, AJ .
DERMATOLOGY, 1999, 198 (04) :355-361
[6]   MODEL FOR LASER DOPPLER MEASUREMENTS OF BLOOD-FLOW IN TISSUE [J].
BONNER, R ;
NOSSAL, R .
APPLIED OPTICS, 1981, 20 (12) :2097-2107
[7]  
BRIERS JD, 1982, INVEST OPHTH VIS SCI, V22, P255
[8]   Spectral domain optical coherence tomography - Ultra-high speed, ultra-high resolution ophthalmic imaging [J].
Chen, TC ;
Cense, B ;
Pierce, MC ;
Nassif, N ;
Park, BH ;
Yun, SH ;
White, BR ;
Bouma, BE ;
Tearney, GJ ;
de Boer, JF .
ARCHIVES OF OPHTHALMOLOGY, 2005, 123 (12) :1715-1720
[9]   Improved signal-to-noise ratio in spectral-domain compared with time-domain optical coherence tomography [J].
de Boer, JF ;
Cense, B ;
Park, BH ;
Pierce, MC ;
Tearney, GJ ;
Bouma, BE .
OPTICS LETTERS, 2003, 28 (21) :2067-2069
[10]   Real-time phase-resolved optical coherence tomography and optical Doppler tomography [J].
Ding, ZH ;
Zhao, YH ;
Ren, HW ;
Nelson, JS ;
Chen, ZP .
OPTICS EXPRESS, 2002, 10 (05) :236-245