Arginine methylation regulates the cytokine response

被引：8

作者：

Boisvert, FM ^{[1
]}

Richard, S

机构：

[1] McGill Univ, Lady Davis Inst Med Res, Terry Fox Mol Oncol Grp, Dept Oncol, Montreal, PQ H3T 1E2, Canada

[2] McGill Univ, Lady Davis Inst Med Res, Terry Fox Mol Oncol Grp, Dept Med, Montreal, PQ H3T 1E2, Canada

[3] McGill Univ, Lady Davis Inst Med Res, Bloomfield Ctr Res Aging, Dept Oncol, Montreal, PQ H3T 1E2, Canada

[4] McGill Univ, Lady Davis Inst Med Res, Bloomfield Ctr Res Aging, Dept Med, Montreal, PQ H3T 1E2, Canada

来源：

MOLECULAR CELL | 2004年 / 15卷 / 04期

关键词：

D O I：

10.1016/j.molcel.2004.08.011

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The recent identification of the NFAT-interacting protein NIP45 as a methylated protein by Mowen et al. (2004) marks a new role for protein arginine methylation in lymphocyte signaling and cytokine gene activation.

引用

页码：492 / 494

页数：3

共 9 条

[1] Ordered cooperative functions of PRMT1, p300, and CARM1 in transcriptional activation by p53 [J].

An, W ;

Kim, J ;

Roeder, RG .

CELL, 2004, 117 (06) :735-748

[2] A proteomic analysis of arginine-methylated protein complexes [J].

Boisvert, FM ;

Côté, J ;

Boulanger, MC ;

Richard, S .

MOLECULAR & CELLULAR PROTEOMICS, 2003, 2 (12) :1319-1330

[3] Methylation of STAT6 modulates STAT6 phosphorylation, nuclear translocation, and DNA-binding activity [J].

Chen, WG ;

Daines, MO ;

Hershey, GKK .

JOURNAL OF IMMUNOLOGY, 2004, 172 (11) :6744-6750

[4] RNA and protein interactions modulated by protein arginine methylation [J].

Gary, JD ;

Clarke, S .

PROGRESS IN NUCLEIC ACID RESEARCH AND MOLECULAR BIOLOGY, VOL 61, 1998, 61 :65-131

[5] Loss of CARM1 results in hypomethylation of thymocyte cyclic AMP-regulated phosphoprotein and deregulated early T cell development [J].

Kim, J ;

Lee, J ;

Yadav, N ;

Wu, Q ;

Carter, C ;

Richard, S ;

Richie, E ;

Bedford, MT .

JOURNAL OF BIOLOGICAL CHEMISTRY, 2004, 279 (24) :25339-25344

[6] State of the Arg: Protein methylation at arginine comes of age [J].

McBride, AE ;

Silver, PA .

CELL, 2001, 106 (01) :5-8

[7] Arginine methylation of NIP45 modulates cytokine gene expression in effector T lymphocytes [J].

Mowen, KA ;

Schurter, BT ;

Fathman, JW ;

David, M ;

Glimcher, LH .

MOLECULAR CELL, 2004, 15 (04) :559-571

[8] Arginine methylation of STAT1 modulates IFNα/β-induced transcription [J].

Mowen, KA ;

Tang, J ;

Zhu, W ;

Schurter, BT ;

Shuai, K ;

Herschman, HR ;

David, M .

CELL, 2001, 104 (05) :731-741

[9] Targeted recruitment of a histone H4-specific methyltransferase by the transcription factor YY1 [J].

Rezai-Zadeh, N ;

Zhang, XH ;

Namour, F ;

Fejer, G ;

Wen, YD ;

Yao, YL ;

Gyory, I ;

Wright, K ;

Seto, E .

GENES & DEVELOPMENT, 2003, 17 (08) :1019-1029

← 1 →