History of hematopoietic cell transplantation: challenges and progress

被引：82

作者：

Granot, Noa ^{[1
,2
]}

Storb, Rainer ^{[1
,2
]}

机构：

[1] Fred Hutchinson Canc Res Ctr, 1124 Columbia St, Seattle, WA 98104 USA

[2] Univ Washington, Seattle, WA 98195 USA

来源：

HAEMATOLOGICA | 2020年 / 105卷 / 12期

关键词：

VERSUS-HOST-DISEASE; BONE-MARROW-TRANSPLANTATION; TOTAL-BODY IRRADIATION; SEVERE APLASTIC-ANEMIA; TERM-FOLLOW-UP; SEVERE COMBINED IMMUNODEFICIENCY; CORD-BLOOD TRANSPLANTATION; HLA-IDENTICAL SIBLINGS; ACUTE MYELOID-LEUKEMIA; PERIPHERAL-BLOOD;

D O I：

10.3324/haematol.2019.245688

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

After more than 60 years of research in allogeneic hematopoietic cell transplantation (HCT), this therapy has advanced from one that was declared dead in the 1960s to a standard treatment of otherwise fatal malignant and non-malignant blood diseases. To date, close to 1.5 million hematopoietic cell transplants have been performed in more than 1,500 transplantation centers worldwide. This review will highlight the enormous efforts by numerous investigators throughout the world who have brought the experimental field of HCT to clinical reality, examine ongoing challenges, and provide insights for the future.

引用

页码：2716 / 2729

页数：14

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