Room temperature hydroamination of N-alkenyl ureas catalyzed by a gold(I) N-heterocyclic carbene complex

被引：135

作者：

Bender, Christopher F. ^{[1
]}

Widenhoefer, Ross A. ^{[1
]}

机构：

[1] Duke Univ, PM Gross Chem Lab, Durham, NC 27708 USA

来源：

ORGANIC LETTERS | 2006年 / 8卷 / 23期

关键词：

D O I：

10.1021/ol062107i

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

[GRAPHICS] Treatment of an N-4-pentenyl or N-5-hexenyl urea with a catalytic 1: 1 mixture of a gold(I) N,N-diarylimidazol-2-ylidine complex and AgOTf at or near room temperature leads to intramolecular exo-hydroamination to form the corresponding nitrogen heterocycle in excellent yield.

引用

页码：5303 / 5305

页数：3

共 39 条

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