The use of microorganisms in L-ascorbic acid production

被引：120

作者：

Bremus, Christoph ^{[1
]}

Herrmann, Ute ^{[1
]}

Bringer-Meyer, Stephanie ^{[1
]}

Sahm, Hermann ^{[1
]}

机构：

[1] Forschungszentrum Julich GmbH, Inst Biotechnol 1, D-52425 Julich, Germany

来源：

JOURNAL OF BIOTECHNOLOGY | 2006年 / 124卷 / 01期

关键词：

vitamin C; L-ascorbic acid; 2-keto-L-gulonic acid;

D O I：

10.1016/j.jbiotec.2006.01.010

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

L-Ascorbic acid has been industrially produced for around 70 years. Over the past two decades, several innovative bioconversion systems have been proposed in order to simplify the long time market-dominating Reichstein method, a largely chemical synthesis by which still a considerable part Of L-ascorbic acid is produced. Here, we describe the current state of biotechnological alternatives using bacteria, yeasts, and microalgae. We also discuss the potential for direct production Of L-ascorbic acid exploiting novel bacterial pathways. The advantages of these novel approaches competing with current chemical and biotechnological processes are outlined. (c) 2006 Elsevier B.V. All rights reserved.

引用

页码：196 / 205

页数：10

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