Stereodivergent and regioselective synthesis of 3,4-cis- and 3,4-trans-pyrrolidinediols from α-amino acids

被引：19

作者：

Kim, JH

Long, MJC

Kim, JY

Park, KH ^{[1
]}

机构：

[1] Gyeongsang Natl Univ, Div Appl Life Sci, Program Bk21, Dept Agr Chem, Jinju, South Korea

[2] Univ Oxford, Chem Res Lab, Oxford OX1 3TA, England

来源：

ORGANIC LETTERS | 2004年 / 6卷 / 13期

关键词：

D O I：

10.1021/ol049237g

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

[GRAPHICS] Highly stereodivergent Woodward-Prevost reaction applied to iodoacetates derived from homochiral alpha-amino acids afforded enantiopure 3,4-cis- and 3,4-trans-pyrrolidinediol derivatives, with control over the protecting group, allowing for differential protection.

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页码：2273 / 2276

页数：4

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