Enteral nutrition and infections: the role of human milk

被引:16
作者
Civardi, Elisa [1 ,2 ]
Garofoli, Francesca [3 ]
Mazzucchelli, Iolanda [3 ,4 ]
Angelini, Micol [3 ]
Manzoni, Paolo [5 ]
Stronati, Mauro [1 ,2 ,3 ]
机构
[1] Fdn IRCCS Policlin San Matteo, Neonatal Unit, I-27100 Pavia, Italy
[2] Fdn IRCCS Policlin San Matteo, Neonatal Intens Care Unit, I-27100 Pavia, Italy
[3] Fdn IRCCS Policlin San Matteo, Neonatal Intens Care Unit, Neonatal Immunol Lab, I-27100 Pavia, Italy
[4] Univ Pavia, Dep Internal Med & Therapeut, I-27100 Pavia, Italy
[5] St Anna Hosp, Neonatol & NICU, Turin, Italy
关键词
Neonatal infection; Human milk; Bioactive constituents; Enteral nutrition; RANDOMIZED CONTROLLED-TRIAL; INTENSIVE-CARE-UNIT; FORMULA-FED INFANTS; BREAST-MILK; DIETARY NUCLEOTIDES; OLIGOSACCHARIDES; PREVENTION; MOTHERS; GROWTH;
D O I
10.1016/S0378-3782(14)70019-2
中图分类号
R71 [妇产科学];
学科分类号
100211 [妇产科学];
摘要
Human milk (HM) is known as the best nutrition for newborns and support the optimal growth of infants, providing essential substances, nutrients, bioactive and immunologic constituents. HM also grants a favorable microbial colonization with attendant priming/maturation of the gut. The bioactive and immunologic elements of HM demonstrated to protect offspring against infection and inflammation and contribute to immune maturation. Some of these elements are being investigated in order to be used to ameliorate formula milk. A formula milk similar to breast milk may help neonatal gut to build a microbiota near to the one of the breast fed infants, improving the neonate's protection against pathogens. The aim of this review is to summarize the most significant bioactive constituents of HM that own natural anti-infectious properties and contribute to neonatal immune defense. (C) 2014 Elsevier Ireland Ltd. All rights reserved.
引用
收藏
页码:S57 / S59
页数:3
相关论文
共 21 条
[1]
American Society of Pediatrics, 2012, PEDIATRICS, V129, pe827
[2]
Strategies for the prevention of hospital-acquired infections in the neonatal intensive care unit [J].
Borghesi, A. ;
Stronati, M. .
JOURNAL OF HOSPITAL INFECTION, 2008, 68 (04) :293-300
[3]
Microbial ecology and host-microbiota interactions during early life stages [J].
Carmen Collado, Maria ;
Cernada, Maria ;
Bauerl, Christine ;
Vento, Maximo ;
Perez-Martinez, Gaspar .
GUT MICROBES, 2012, 3 (04) :352-365
[4]
Escherichia coli specific secretory IgA and cytokines in human milk from mothers of different ethnic groups resident in northern italy [J].
Ciardelli, L. ;
Garofoli, F. ;
Avanzini, M. A. ;
De Silvestri, A. ;
Gasparoni, A. ;
Sabatin, G. ;
Stronati, M. .
INTERNATIONAL JOURNAL OF IMMUNOPATHOLOGY AND PHARMACOLOGY, 2007, 20 (02) :335-340
[5]
Pasteurization of Mother's Own Milk for Preterm Infants Does Not Reduce the Incidence of Late-Onset Sepsis [J].
Cossey, Veerle ;
Vanhole, Chris ;
Eerdekens, An ;
Rayyan, Maissa ;
Fieuws, Steffen ;
Schuermans, Annette .
NEONATOLOGY, 2013, 103 (03) :170-176
[6]
Prebiotic oligosaccharides: In vitro evidence for gastrointestinal epithelial transfer and immunomodulatory properties [J].
Eiwegger, Thomas ;
Stahl, Bernd ;
Haidl, Paul ;
Schmitt, Joachim ;
Boehm, Gunther ;
Dehlink, Eleonora ;
Urbanek, Radvan ;
Szepfalusi, Zsolt .
PEDIATRIC ALLERGY AND IMMUNOLOGY, 2010, 21 (08) :1179-1188
[7]
Effect of providing a formula supplemented with long-chain polyunsaturated fatty acids on immunity in full-term neonates [J].
Field, Catherine J. ;
Van Aerdel, John E. ;
Robinson, Lindsay E. ;
Clandinin, M. Thomas .
BRITISH JOURNAL OF NUTRITION, 2008, 99 (01) :91-99
[8]
The Impact of Dietary Long-Chain Polyunsaturated Fatty Acids on Respiratory Illness in Infants and Children [J].
Hageman, Jeske H. J. ;
Hooyenga, Pieter ;
Diersen-Schade, Deborah A. ;
Scalabrin, Deolinda M. Felin ;
Wichers, Harry J. ;
Birch, Eileen E. .
CURRENT ALLERGY AND ASTHMA REPORTS, 2012, 12 (06) :564-573
[9]
Protective effect of exclusive breastfeeding against infections during infancy: a prospective study [J].
Ladomenou, Fani ;
Moschandreas, Joanna ;
Kafatos, Anthony ;
Tselentis, Yiannis ;
Galanakis, Emmanouil .
ARCHIVES OF DISEASE IN CHILDHOOD, 2010, 95 (12) :1004-1008
[10]
Beneficial effects of probiotic bacteria isolated from breast milk [J].
Lara-Villoslada, Federico ;
Olivares, Monica ;
Sierra, Saleta ;
Miguel Rodriguez, Juan ;
Boza, Julio ;
Xaus, Jordi .
BRITISH JOURNAL OF NUTRITION, 2007, 98 :S96-S100