The awesome power of yeast biochemical genomics

被引:8
作者
Carlson, M [1 ]
机构
[1] Columbia Univ, Dept Genet & Dev, New York, NY 10032 USA
关键词
D O I
10.1016/S0168-9525(99)01948-4
中图分类号
Q3 [遗传学];
学科分类号
071007 ; 090102 ;
摘要
A new genomic strategy for identifying the gene encoding any biochemical activity has recently been developed, in which an array of individual yeast strains expressing a genomic set of open reading frames fused to glutathione S-transferase can be assayed for a biochemical activity of interest. Designated 'biochemical genomics', this approach represents an innovative application of genomic information.
引用
收藏
页码:49 / 51
页数:3
相关论文
共 3 条
[1]  
Fink G.R., 1970, METHODS ENZYMOL VOL, V17, P59, DOI 10.1016/0076-6879(71)17167-4
[2]   BIOCHEMICAL GENETICS OF YEAST [J].
HARTWELL, LH .
ANNUAL REVIEW OF GENETICS, 1970, 4 :373-+
[3]   A biochemical genomics approach for identifying genes by the activity of their products [J].
Martzen, MR ;
McCraith, SM ;
Spinelli, SL ;
Torres, FM ;
Fields, S ;
Grayhack, EJ ;
Phizicky, EM .
SCIENCE, 1999, 286 (5442) :1153-1155