Distribution of thromboxane A(2) receptor mRNA along the mouse nephron segments

被引：8

作者：

Asano, K ^{[1
]}

Taniguchi, S ^{[1
]}

Nakao, A ^{[1
]}

Maruyama, T ^{[1
]}

Watanabe, T ^{[1
]}

Kurokawa, K ^{[1
]}

机构：

[1] UNIV TOKYO,FAC MED,DEPT INTERNAL MED 1,TOKYO 113,JAPAN

来源：

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 1996年 / 226卷 / 03期

关键词：

D O I：

10.1006/bbrc.1996.1404

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Thromboxane A(2) (TXA(2)) receptor mRNA was semi-quantitated in microdissected mouse nephron segments by reverse transcription-polymerase chain reaction (RT-PCR). TXA(2) receptor mRNA was most abundantly expressed in the glomerulus, followed by the distal convoluted tubule > proximal tubule, thick ascending limb of Henle, and outer medullary collecting duct. These results suggest the potential physiological roles of TXA(2) in the entire renal tubule as well as in the glomerulus. (C) 1996 Academic Press, Inc.

引用

收藏

页码：613 / 617

页数：5

相关论文

共 19 条

[1] RAT KIDNEY THROMBOXANE RECEPTOR - MOLECULAR-CLONING, SIGNAL-TRANSDUCTION, AND INTRARENAL EXPRESSION LOCALIZATION [J].

ABE, T ;

TAKEUCHI, K ;

TAKAHASHI, N ;

TSUTSUMI, E ;

TANIYAMA, Y ;

ABE, K .

JOURNAL OF CLINICAL INVESTIGATION, 1995, 96 (02) :657-664

[2] VASOCONSTRICTOR EVOKED PROSTAGLANDIN SYNTHESIS IN CULTURED HUMAN MESANGIAL CELLS [J].

ARDAILLOU, N ;

HAGEGE, J ;

NIVEZ, MP ;

ARDAILLOU, R ;

SCHLONDORFF, D .

AMERICAN JOURNAL OF PHYSIOLOGY, 1985, 248 (02) :F240-F246

[3] Distribution of platelet activating factor receptor mRNA along the rat nephron segments [J].

Asano, K ;

Taniguchi, S ;

Nakao, A ;

Watanabe, T ;

Kurokawa, K .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1996, 225 (02) :352-357

[4] GLOMERULAR RESPONSES TO PLATELET-ACTIVATING FACTOR IN THE RAT - ROLE OF THROMBOXANE-A2 [J].

BADR, KF ;

DEBOER, DK ;

TAKAHASHI, K ;

HARRIS, RC ;

FOGO, A ;

JACOBSON, HR .

AMERICAN JOURNAL OF PHYSIOLOGY, 1989, 256 (01) :F35-F43

[5] PLATELET-ACTIVATING-FACTOR INHIBITS CL AND K TRANSPORT IN THE MEDULLARY THICK ASCENDING LIMB [J].

BAILLY, C ;

BARLETBAS, C ;

AMIEL, C .

KIDNEY INTERNATIONAL, 1992, 41 (02) :269-274

[6] Localization of authentic thromboxane A(2)/prostaglandin H-2 receptor in the rat kidney [J].

Bresnahan, BA ;

LeBreton, GC ;

Lianos, EA .

KIDNEY INTERNATIONAL, 1996, 49 (05) :1207-1213

[7] THROMBOXANE-A2 AND PROSTAGLANDIN ENDOPEROXIDE ANALOG EFFECTS ON PORCINE RENAL BLOOD-FLOW [J].

CIRINO, M ;

MORTON, H ;

MACDONALD, C ;

HADDEN, J ;

FORDHUTCHINSON, AW .

AMERICAN JOURNAL OF PHYSIOLOGY, 1990, 258 (01) :F109-F114

[8] CLONING AND EXPRESSION OF CDNA FOR A HUMAN THROMBOXANE-A2 RECEPTOR [J].

HIRATA, M ;

HAYASHI, Y ;

USHIKUBI, F ;

YOKOTA, Y ;

KAGEYAMA, R ;

NAKANISHI, S ;

NARUMIYA, S .

NATURE, 1991, 349 (6310) :617-620

[9] DISTRIBUTION OF 1,25-DIHYDROXYVITAMIN-D(3) RECEPTOR AND 25-HYDROXYVITAMIN-D(3)-24-HYDROXYLASE MESSENGER-RNA EXPRESSION ALONG RAT NEPHRON SEGMENTS [J].

IIDA, K ;

TANIGUCHI, S ;

KUROKAWA, K .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1993, 194 (02) :659-664

[10] CONTRACTILE EFFECTS OF TXA2 AND ENDOPEROXIDE ANALOGS ON CULTURED RAT GLOMERULAR MESANGIAL CELLS [J].

MENE, P ;

DUNN, MJ .

AMERICAN JOURNAL OF PHYSIOLOGY, 1986, 251 (06) :F1029-F1035