Cutaneous blood flow increases in the rat hindpaw during dorsal column stimulation

被引：16

作者：

Croom, JE ^{[1
]}

Barron, KW ^{[1
]}

Chandler, MJ ^{[1
]}

Foreman, RD ^{[1
]}

机构：

[1] UNIV OKLAHOMA, HLTH SCI CTR, DEPT PHYSIOL, OKLAHOMA CITY, OK 73190 USA

来源：

BRAIN RESEARCH | 1996年 / 728卷 / 02期

关键词：

dorsal column stimulation; spinal cord stimulation; laser Doppler; skin vasodilation; microcirculation; spinal cord;

D O I：

10.1016/S0006-8993(96)00554-9

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

The purpose of this study was to determine the optimal stimulation site and parameters that result in the greatest changes in cutaneous blood flow during dorsal column stimulation (DCS). Laser Doppler flowmetry was used to assess cutaneous blood flow changes in both rat hindpaws during DCS with a unipolar ball electrode. We found that stimulating the dorsal column at the L(2) spinal segment at 0.6 mA at either 25 or 50 Hz with a pulse duration of 0.2 ms resulted in the largest cutaneous blood flow increases in the rat hindpaw. In addition, the DCS response appeared to be limited primarily to the hindpaw ipsilateral to the site of DCS.

引用

页码：281 / 286

页数：6

共 18 条

[1] EPIDURAL ELECTRICAL-STIMULATION IN SEVERE LIMB ISCHEMIA - PAIN RELIEF, INCREASED BLOOD-FLOW, AND A POSSIBLE LIMB-SAVING EFFECT [J].

AUGUSTINSSON, LE ;

CARLSSON, CA ;

HOLM, J ;

JIVEGARD, L .

ANNALS OF SURGERY, 1985, 202 (01) :104-110

[2]

BROSETA J, 1985, APPL NEUROPHYSIOL, V48, P367

[3] SPINAL-CORD STIMULATION IN PERIPHERAL ARTERIAL-DISEASE - A COOPERATIVE STUDY [J].

BROSETA, J ;

BARBERA, J ;

DEVERA, JA ;

BARCIASALORIO, JL ;

GARCIAMARCH, G ;

GONZALEZDARDER, J ;

ROVAINA, F ;

JOANES, V .

JOURNAL OF NEUROSURGERY, 1986, 64 (01) :71-80

[4]

BUNT TJ, 1991, SEMIN VASC SURG, V4, P216

[5]

COOK AW, 1976, NEW YORK STATE J MED, V76, P366

[6]

Horsch S, 1994, Ann Vasc Surg, V8, P468

[7]

JACOBS MJH, 1990, VASC MED REV, V1, P215

[8] FOOT SALVAGE AND IMPROVEMENT OF MICROVASCULAR BLOOD-FLOW AS A RESULT OF EPIDURAL SPINAL-CORD ELECTRICAL-STIMULATION [J].

JACOBS, MJHM ;

JORNING, PJG ;

BECKERS, RCY ;

UBBINK, DT ;

VANKLEEF, M ;

SLAAF, DW ;

RENEMAN, RS .

JOURNAL OF VASCULAR SURGERY, 1990, 12 (03) :354-360

[9] SYMPATHETIC MEDIATION OF PERIPHERAL VASODILATION INDUCED BY SPINAL-CORD STIMULATION - ANIMAL STUDIES OF THE ROLE OF CHOLINERGIC AND ADRENERGIC-RECEPTOR SUBTYPES [J].

LINDEROTH, B ;

HERREGODTS, P ;

MEYERSON, BA .

NEUROSURGERY, 1994, 35 (04) :711-719

[10] PERIPHERAL VASODILATATION AFTER SPINAL-CORD STIMULATION - ANIMAL STUDIES OF PUTATIVE EFFECTOR MECHANISMS [J].

LINDEROTH, B ;

FEDORCSAK, I ;

MEYERSON, BA .

NEUROSURGERY, 1991, 28 (02) :187-195

← 1 2 →