Two novel furostanol saponins from the tubers of Ophiopogon japonicus

被引：9

作者：

Guo, Yu ^{[1
]}

Liu, Yi-Xun ^{[1
,2
]}

Kang, Li-Ping ^{[2
,3
]}

Zhang, Tao ^{[2
]}

Yu, He-Shui ^{[2
,3
]}

Zhao, Yang ^{[2
]}

Xiong, Cheng-Qi ^{[2
]}

Ma, Bai-Ping ^{[2
]}

机构：

[1] Univ South China, Inst Pharm & Pharmacol, Learning Key Lab Pharmacoprote Hunan Prov, Hengyang 421001, Peoples R China

[2] Beijing Inst Radiat Med, Beijing 100850, Peoples R China

[3] Tianjin Univ Tradit Chinese Med, Tianjin 300193, Peoples R China

来源：

JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH | 2013年 / 15卷 / 05期

关键词：

Ophiopogon japonicus; furostanol saponin; ophiopogonin P; ophiopogonin Q; STEROIDAL SAPONINS; UNDERGROUND PARTS; SAPOGENINS; GLYCOSIDES; RHIZOMES; SEEDS;

D O I：

10.1080/10286020.2013.783024

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Phytochemical investigation of the fresh tubers of Ophiopogon japonicus led to the isolation of two new furostanol saponins (1 and 2) together with two known steroidal saponins (3 and 4). Comprehensive spectroscopic analysis allowed the chemical structures of two new compounds to be elucidated as (25R)-26-O-[-d-glucopyranosyl-(12)--d-glucopyranosyl]-5-ene-furost-1,3,22,26-tetraol-3-O--l-rhamnopyranosyl-(12)-[-d-xylopyranosyl-(14)]--d-glucopyranoside (1, ophiopogonin P) and (25R)-26-O-[-d-glucopyranosyl-(16)--d-glucopyranosyl]-5-ene-furost-1,3,22,26-tetraol-3-O--l-rhamnopyranosyl-(12)-[-d-xylopyranosyl-(14)]--d-glucopyranoside (2, ophiopogonin Q). Furostanol saponins with the disaccharide chain linked at C-26 hydroxy group of the aglycone have been rarely reported from natural sources.

引用

页码：459 / 465

页数：7

共 19 条

[1] Furostane-Type Steroidal Saponins from the Roots of Chlorophytum borivilianum [J].

Acharya, Debabrata ;

Mitaine-Offer, Anne-Claire ;

Kaushik, Nutan ;

Miyamoto, Tomofumi ;

Paululat, Thomas ;

Lacaille-Dubois, Marie-Aleth .

HELVETICA CHIMICA ACTA, 2008, 91 (12) :2262-2269

[2] Assigning stereodiversity of the 27-Me group of furostane-type steroidal saponins via NMR chemical shifts [J].

Agrawal, PK .

STEROIDS, 2005, 70 (10) :715-724

[3] NMR spectroscopy of steroidal sapogenins and steroidal saponins: An update [J].

Agrawal, PK ;

Jain, DC ;

Pathak, AK .

MAGNETIC RESONANCE IN CHEMISTRY, 1995, 33 (12) :923-953

[4] Steroidal glycosides from the underground parts of Helleborus caucasicus [J].

Bassarello, Carla ;

Muzashvili, Tamara ;

Skhirtladze, Alexandre ;

Kemertelidze, Ether ;

Pizza, Cosimo ;

Piacente, Sonia .

PHYTOCHEMISTRY, 2008, 69 (05) :1227-1233

[5] NMR assignment of the absolute configuration of C-25 in furostanol steroidal saponins [J].

Challinor, Victoria L. ;

Piacente, Sonia ;

De Voss, James J. .

STEROIDS, 2012, 77 (06) :602-608

[6] Furostanol saponins in Allium caepa L. var. tropeana seeds [J].

Dini, I ;

Tenore, GC ;

Trimarco, E ;

Dini, A .

FOOD CHEMISTRY, 2005, 93 (02) :205-214

[7] A new steroidal saponin from the seeds of Allium tuberosum [J].

Hu, Guohua ;

Mao, Rengang ;

Ma, Zhengzhi .

FOOD CHEMISTRY, 2009, 113 (04) :1066-1068

[8]

Jiang FR, 2006, CHIN ARCH TRADIT CHI, V24, P236

[9]

Kang L. P., 2012, CHIN J MAGN RESON, V29, P1

[10] Acylated triterpene saponins from the roots of Securidaca longepedunculata [J].

Mitaine-Offer, Anne-Claire ;

Penez, Nicolas ;

Miyamoto, Tomofumi ;

Delaude, Clement ;

Mirjolet, Jean-Francois ;

Duchamp, Olivier ;

Lacaille-Dubois, Marie-Aleth .

PHYTOCHEMISTRY, 2010, 71 (01) :90-94

← 1 2 →