Transcription termination and anti-termination in E-coli

被引:167
作者
Nudler, E [1 ]
Gottesman, ME
机构
[1] NYU Med Ctr, Dept Biochem, New York, NY 10016 USA
[2] Columbia Univ Coll Phys & Surg, Inst Canc Res, New York, NY 10032 USA
关键词
D O I
10.1046/j.1365-2443.2002.00563.x
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
Transcription termination in Escherichia coli is controlled by many factors. The sequence of the DNA template, the structure of the transcript, and the actions of auxiliary proteins all play a role in determining the efficiency of the process. Termination is regulated and can be enhanced or suppressed by host and phage proteins. This complex reaction is rapidly yielding to biochemical and structural analysis of the interacting factors. Below we review and attempt to unify into basic principles the remarkable recent progress in understanding transcription termination and anti-termination.
引用
收藏
页码:755 / 768
页数:14
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