A functional magnetic resonance imaging study of episodic memory

被引：17

作者：

Busatto, G

Howard, RJ

Ha, Y

Brammer, M

Wright, I

Woodruff, PWR

Simmons, A

Williams, SCR

David, AS

Bullmore, ET

机构：

[1] INST PSYCHIAT,OLD AGE PSYCHIAT SECT,LONDON SE5 8AF,ENGLAND

[2] INST PSYCHIAT,DEPT PSYCHOL MED,LONDON SE5 8AF,ENGLAND

[3] INST PSYCHIAT,DEPT BIOSTAT & COMP,LONDON SE5 8AF,ENGLAND

[4] INST PSYCHIAT,DEPT NEUROIMAGING,LONDON SE5 8AF,ENGLAND

来源：

NEUROREPORT | 1997年 / 8卷 / 12期

关键词：

encoding; episodic memory; fMRI; functional connectivity; retrieval;

D O I：

10.1097/00001756-199708180-00007

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

We have used whole brain fMRI and canonical variate analysis to investigate the anatomical location of brain activity subserving episodic memory encoding and recognition. Recognition of previously presented words did not specifically activate right prefrontal areas although right-sided activations were seen during transitions between the target and reference phases of the paradigm. Encoding was associated with left sided prefrontal activation, but this was within Broca's area rather than dorsolateral prefrontal cortex. The temporal resolution of fMRI, combined with analysis of the apparent functional connectivity of activations observed, revealed activity within complex networks each functionally specialized for the demands of particular aspects of a cognitive task.

引用

页码：2671 / 2675

页数：5

共 25 条

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ADCOCK RA, 1996, NEUROIMAGE, V3, pS526

[2]

AGUIRRE NC, 1996, NEUROIMAGE, V3, pS527

[3] SHORT-TERM AND LONG-TERM VERBAL MEMORY - A POSITRON EMISSION TOMOGRAPHY STUDY [J].