Cooling the burn wound: evaluation of different modalites

被引:113
作者
Jandera, V [1 ]
Hudson, DA [1 ]
de Wet, PM [1 ]
Innes, PM [1 ]
Rode, H [1 ]
机构
[1] Univ Cape Town, Dept Paediat Surg, ZA-7925 Cape Town, South Africa
关键词
burns; first aid; cooking;
D O I
10.1016/S0305-4179(99)00133-3
中图分类号
R4 [临床医学];
学科分类号
1002 ; 100602 ;
摘要
A study was undertaken to investigate the cooling and healing effect of different modalities: Melaleuca Alternifolia Hydrogel (Levtrade international (Pty) Ltd.) was compared with lap water as a coolant following application onto a fresh deep partial thickness hot water burn in a porcine model. Four identical circular scalds were created on the backs of 10 pigs. One wound was not treated and served as a control. The other 3 wounds were either cooled with tap water (15 degrees C) or had Melaleuca Hydrogel dressing applied immediately, or after a 30 min delay. Intradermal temperatures were monitored in all wounds: preburn, during the burn and at regular intervals for 1 h, The wounds were biopsied for histological assessment. These samples were repeated at 24 h and 3 weeks, The mean decrease in final temperature at 1 h was in comparison to the preburn temperature: control + 0.44 degrees C (i.e. a temperature increase); water -7.82 degrees C; Melaleuca Hydrogel -3.87 degrees C; Melaleuca Hydrogel after 30 min delay -2.67 degrees C. Clinical and histological assessment at 21 days indicated more rapid healing in both the Melaleuca Hydrogel and water-cooled burns compared with the untreated controls. Effective cooling of the burn wound and an increased rate of wound healing was achieved by both repeated tap water compresses and by immediate or delayed application of Melaleuca Hydrogel. Cooling is an effective means to reduce tissue damage and increase wound healing. 2000 Elsevier Science Ltd and ISBI, All rights reserved.
引用
收藏
页码:265 / 270
页数:6
相关论文
共 24 条
[1]  
Altman P, 1988, AUST J PHARM, V69, P276
[2]  
Boykin J V Jr, 1981, Curr Surg, V38, P393
[3]   COLD-WATER TREATMENT OF SCALD INJURY AND INHIBITION OF HISTAMINE-MEDIATED BURN EDEMA [J].
BOYKIN, JV ;
ERIKSSON, E ;
SHOLLEY, MM ;
PITTMAN, RN .
JOURNAL OF SURGICAL RESEARCH, 1981, 31 (02) :111-123
[4]   HISTOPATHOLOGICAL EVALUATION OF SCALDS AND CONTACT BURNS IN THE PIG MODEL [J].
BRANS, TA ;
DUTRIEUX, RP ;
HOEKSTRA, MJ ;
KREIS, RW ;
DUPONT, JS .
BURNS, 1994, 20 :S48-S51
[5]   PROMPT COOLING OF BURNED AREAS - A REVIEW OF BENEFITS AND THE EFFECTOR MECHANISMS [J].
DAVIES, JWL .
BURNS, 1982, 9 (01) :1-6
[6]   ULTRASTRUCTURAL ASPECTS OF COOLED THERMAL-INJURY [J].
DECAMARA, DL ;
RAINE, T ;
ROBSON, MC .
JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE, 1981, 21 (11) :911-919
[7]   PROGRESSION OF THERMAL-INJURY - A MORPHOLOGIC STUDY [J].
DECAMARA, DL ;
RAINE, TJ ;
LONDON, MD ;
ROBSON, MC ;
HEGGERS, JP .
PLASTIC AND RECONSTRUCTIVE SURGERY, 1982, 69 (03) :491-499
[8]   EFFECT OF IMMEDIATE AND DELAYED COLD IMMERSION ON BURN EDEMA FORMATION AND RESORPTION [J].
DEMLING, RH ;
MAZESS, RB ;
WOLBERG, W .
JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE, 1979, 19 (01) :56-60
[9]  
Heggars JP, 1982, J BURN CARE REHABIL, V3, P350
[10]   THE EFFECT OF PROMPT LOCAL COOLING ON EDEMA FORMATION IN SCALDED RAT PAWS [J].
JAKOBSSON, OP ;
ARTURSON, G .
BURNS, 1985, 12 (01) :8-15