Association genetics of complex traits in conifers

被引:385
作者
Neale, DB [1 ]
Savolainen, O
机构
[1] USDA, Inst Forest Genet, Forest Serv, Davis, CA 95616 USA
[2] Univ Calif Davis, Dept Environm Hort, Davis, CA 95616 USA
[3] Oulu Univ, Dept Biol, Oulu, Finland
基金
芬兰科学院; 美国国家科学基金会;
关键词
D O I
10.1016/j.tplants.2004.05.006
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
Association studies are becoming the experimental approach of choice to dissect complex traits in many organisms from humans to model plant systems. The candidate gene based-association approach has several important advantages for complex trait dissection in many coniferous forest tree species, including random mating and unstructured populations, adequate levels of nucleotide diversity, rapid decay of linkage disequilibrium, and precise evaluation of phenotype from clonal or progeny testing. Allele discovery using association approaches should lead to more-efficient methods of marker-assisted breeding and a deeper understanding of genetic adaptation in forest trees.
引用
收藏
页码:325 / 330
页数:6
相关论文
共 69 条
[1]   Population dynamics of Pinus taeda L. based on nuclear microsatellites [J].
Al-Rabab'ah, MA ;
Williams, CG .
FOREST ECOLOGY AND MANAGEMENT, 2002, 163 (1-3) :263-271
[2]  
[Anonymous], 1998, ECOLOGY BIOGEOGRAPHY
[3]   Patterns of linkage disequilibrium in the human genome [J].
Ardlie, KG ;
Kruglyak, L ;
Seielstad, M .
NATURE REVIEWS GENETICS, 2002, 3 (04) :299-309
[4]   Clines in polygenic traits [J].
Barton, NH .
GENETICS RESEARCH, 1999, 74 (03) :223-236
[5]  
Beaumont MA., 1996, Proceedings of the Royal Society of London B, V263, P1619, DOI DOI 10.1098/RSPB.1996.0237
[6]   The impact of genomics on the study of natural variation in Arabidopsis [J].
Borevitz, JO ;
Nordborg, M .
PLANT PHYSIOLOGY, 2003, 132 (02) :718-725
[7]   Discovering genotypes underlying human phenotypes: past successes for mendelian disease, future approaches for complex disease [J].
Botstein, D ;
Risch, N .
NATURE GENETICS, 2003, 33 (Suppl 3) :228-237
[8]   Genetic dissection of transcriptional regulation in budding yeast [J].
Brem, RB ;
Yvert, G ;
Clinton, R ;
Kruglyak, L .
SCIENCE, 2002, 296 (5568) :752-755
[9]  
Brown GR, 2003, GENETICS, V164, P1537
[10]   Plant molecular diversity and applications to genomics [J].
Buckler, ES ;
Thornsberry, JM .
CURRENT OPINION IN PLANT BIOLOGY, 2002, 5 (02) :107-111