Preparation of artificial glycolipids and their aggregation behavior in aqueous media

被引：3

作者：

Hisaeda, Y ^{[1
]}

Ohshima, E ^{[1
]}

Kikuchi, J ^{[1
]}

Murakami, Y ^{[1
]}

机构：

[1] KYUSHU UNIV,INST FUNDAMENTAL RES ORGAN CHEM,FUKUOKA 81281,JAPAN

来源：

TETRAHEDRON LETTERS | 1997年 / 38卷 / 38期

关键词：

D O I：

10.1016/S0040-4039(97)01572-4

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

N,N-Dihexadecyl-N-alpha-[6-(beta D-galactopyranosyl)hexanoyl]-L-alaninamide and N,N-dihexadecyl-N-alpha-[6-{(beta D-galactopyranosyl>(1 --> 4>O-(D-glucopyranosyl)}hexanoyl]-L-alaninamide, which have an amino acid residue interposed between a polar sugar moiety and a hydrophobic double-chain segment individually, were prepared and characterized as novel artificial glycolipids. Morphological studies by means of differential scanning calorimetry and dynamic light scattering as well as electron microscopy clarified that these lipids tend to form stable bilayer membranes by themselves in aqueous media. (C) 1997 Elsevier Science Ltd.

引用

页码：6713 / 6716

页数：4

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