Assessment of the neurogenic rare reaction in small-fiber neuropathies

被引：55

作者：

Bickel, A

Krämer, HH

Hilz, MJ

Birklein, F

Neundörfer, B

Schmelz, M

机构：

[1] Univ Erlangen Nurnberg, Neurol Klin Poliklin, Dept Neurol, D-91054 Erlangen, Germany

[2] Univ Erlangen Nurnberg, Inst Physiol 1, D-91054 Erlangen, Germany

来源：

NEUROLOGY | 2002年 / 59卷 / 06期

关键词：

D O I：

10.1212/WNL.59.6.917

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

To improve sensitivity of the analysis of axon reflex flare reaction, the authors used a laser Doppler scanner and analyzed flare intensity and size induced by histamine iontophoresis simultaneously at the foot and thigh in patients with small-fiber neuropathy (n = 10) and controls (n = 9). Flare size, but not laser Doppler flux, clearly distinguished patients from controls at both locations (p < 0.01) and may be useful for evaluation of small-fiber neuropathies.

引用

收藏

页码：917 / 919

页数：3

相关论文

共 10 条

[1] DIMINISHED FLARE RESPONSE IN NEUROPATHIC DIABETIC-PATIENTS - COMPARISON OF EFFECTS OF SUBSTANCE-P, HISTAMINE, AND CAPSAICIN [J].

ARONIN, N ;

LEEMAN, SE ;

CLEMENTS, RS .

DIABETES, 1987, 36 (10) :1139-1143

[2] THE ACETYLCHOLINE-INDUCED FLARE RESPONSE IN EVALUATION OF SMALL FIBER DYSFUNCTION [J].

BENARROCH, EE ;

LOW, PA .

ANNALS OF NEUROLOGY, 1991, 29 (06) :590-595

[3] FABRY DISEASE - IMPAIRED AUTONOMIC FUNCTION [J].

CABLE, WJL ;

KOLODNY, EH ;

ADAMS, RD .

NEUROLOGY, 1982, 32 (05) :498-502

[4] HUMAN DIABETIC ENDONEURIAL SORBITOL, FRUCTOSE, AND MYOINOSITOL RELATED TO SURAL NERVE MORPHOMETRY [J].

DYCK, PJ ;

SHERMAN, WR ;

HALLCHER, LM ;

SERVICE, FJ ;

OBRIEN, PC ;

GRINA, LA ;

PALUMBO, PJ ;

SWANSON, CJ .

ANNALS OF NEUROLOGY, 1980, 8 (06) :590-596

[5] Intraepidermal nerve fiber density in patients with painful sensory neuropathy [J].

Holland, NR ;

Stocks, A ;

Hauer, P ;

Cornblath, DR ;

Griffin, JW ;

McArthur, JC .

NEUROLOGY, 1997, 48 (03) :708-711

[6]

LOW PA, 1997, CLIN AUTONOMIC DISOR, P179

[7] QUANTITATIVE OBJECTIVE ASSESSMENT OF PERIPHERAL NOCICEPTIVE C-FIBER FUNCTION [J].

PARKHOUSE, N ;

LEQUESNE, PM .

JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 1988, 51 (01) :28-34

[8]

Schmelz M, 1997, J NEUROSCI, V17, P8003

[9] RESPONSE TO INTRADERMAL HISTAMINE IN FAMILIAL DYSAUTONOMIA - A DIAGNOSTIC TEST [J].

SMITH, AA ;

DANCIS, J .

JOURNAL OF PEDIATRICS, 1963, 63 (05) :889-+

[10] Acute effects of substance P and calcitonin gene-related peptide in human skin - A microdialysis study [J].

Weidner, C ;

Klede, M ;

Rukwied, R ;

Lischetzki, G ;

Neisius, U ;

Skov, PS ;

Petersen, LJ ;

Schmelz, M .

JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2000, 115 (06) :1015-1020